> top > docs > PMC:7461420 > spans > 22561-23175 > annotations

PMC:7461420 / 22561-23175 JSONTXT

Annnotations TAB JSON ListView MergeView

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T131 249-254 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T132 323-339 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T133 334-339 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T127 50-54 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T128 76-80 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T129 112-116 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T130 194-198 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T131 402-406 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T132 413-422 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T133 493-497 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T134 598-602 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T256 26-32 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T257 177-185 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T258 244-248 http://purl.obolibrary.org/obo/CLO_0009524 denotes Vero
T259 244-248 http://purl.obolibrary.org/obo/CLO_0050515 denotes Vero
T260 249-254 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T261 299-307 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T262 323-333 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T263 334-351 http://purl.obolibrary.org/obo/CL_0000003 denotes cells and in vivo

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T210 0-11 Chemical denotes Chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T211 386-397 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T23 533-555 http://purl.obolibrary.org/obo/GO_0033578 denotes terminal glycosylation
T24 542-555 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
735 508-512 Gene denotes ACE2 Gene:59272
736 559-563 Gene denotes ACE2 Gene:59272
737 50-58 Species denotes SARS‐CoV Tax:694009
738 62-70 Species denotes MERS‐CoV Tax:1335626
739 76-86 Species denotes SARS‐CoV‐2 Tax:2697049
740 112-122 Species denotes SARS‐CoV‐2 Tax:2697049
741 194-202 Species denotes SARS‐CoV Tax:694009
742 493-501 Species denotes SARS‐CoV Tax:694009
743 598-606 Species denotes SARS‐CoV Tax:694009
744 311-322 Species denotes respiratory Tax:12814
745 0-11 Chemical denotes Chloroquine MESH:D002738
746 386-397 Chemical denotes chloroquine MESH:D002738
747 402-422 Disease denotes SARS‐CoV‐1 infection MESH:C000657245

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T220 0-87 Sentence denotes Chloroquine is reasonably active in vitro against SARS‐CoV‐1, MERS‐CoV, and SARS‐CoV‐2.
T221 88-162 Sentence denotes It was found to inhibit SARS‐CoV‐2 with an EC50 value of 5.47 µM in vitro.
T222 163-352 Sentence denotes 66 Antiviral activity against SARS‐CoV‐1 was reported with an IC50 of 8.8 μM in Vero cells, but it is unclear how this translates into activity in respiratory epithelial cells and in vivo.
T223 353-611 Sentence denotes 67 , 68 Mechanistic studies of chloroquine for SARS‐CoV‐1 infection revealed that it could also weaken the interaction between the RBD of SARS‐CoV‐1 and ACE2 by interfering with terminal glycosylation of ACE2, thereby reducing its affinity to SARS‐CoV‐1 S.
T224 612-614 Sentence denotes 69