Declining appropriations for nutrition-relevant research and statistics at USDA, compounded by declining public investment in agrifood research and development, is limiting the nation's ability to fully understand and leverage the critical nexus between agriculture, food, and health (12, 146, 147). An emphasis on agricultural production research has created pressure on the USDA nutrition portfolio to respond to these growing research needs and opportunities with its limited budget. Strong Congressional appropriations for nutrition research across REE is critical to reestablish the US as the global leader in food and agricultural science and technology, which creates healthy and productive communities, families, and youth. A renewed commitment to advancing and integrating nutrition into the overall crop, livestock, food manufacturing, food safety, natural resources, and climate research agendas has tremendous potential to improve economic growth, national security, competitiveness, sustainability, climate resilience, food security, and public health. Such investment would also maximize cross-governmental coordination and public–private partnerships with the greatest potential to accelerate progress in this complex nexus.