Size and resources of such an office remain relatively limited for substantially needed strategic planning, cross-governmental collaboration, public communication, assistance with the DGAs, DRIs, and national monitoring and surveillance, food and nutrition regulatory activities, and external partnerships Insufficient independent funding to stimulate major extramural or intramural research Inadequate authority and resources to support new national training of scientists and health care professionals Budgets, staff sizes, and influence can vary widely between offices and fluctuate over time