is hampered by the absence of any federal home for its investment and coordination. For example, little is known about the molecular basis of varying nutritional needs across continua from birth to older age, health to disease, or inactive to active lifestyles (11). Pathways of nutritional influences during the first 1000 days of life, when critical metabolic programming can alter lifelong and possibly epigenerational disease risk, remain critically understudied (237). Food allergies have exploded among US children, yet wit