The COVID-19 outbreak continues to evolve, currently with spread throughout the United States, which remains the epicenter of the pandemic. In all areas of medicine, there is a critical need for accurate information to inform an appropriate response to the outbreak. There are an increasing number of clinical studies for COVID-19, but our current understanding in relationship to seizures and epilepsy remains limited by relative lack of cohort studies, especially in patients with preexisting seizures and epilepsy. Realizing both the need for and limitation of current information, this summary provides a focused summary of pertinent clinical diagnostic information about neurological involvement of SARS-CoV-2 virus and COVID-19, especially in relationship to patients with seizures and epilepsy.