The approach employed in SHUR—co-creating measures of salient stressors with communities for which our work bears relevance is important for understanding the mechanisms through which social conditions affect health, the contextual specificity of these mechanisms, and what kinds of interventions might help eliminate health disparities caused by structural inequalities. Measures in the current survey are critical for providing evidence needed to inform policies that would improve health among urbanized populations. We encourage others to use these data. Community-driven approaches to creating measures related to navigating COVID-19 that are salient to the experiences of populations marginalized by structural inequalities are important next steps.