PMC:7443692 / 503-876
Annnotations
LitCovid-sample-CHEBI
{"project":"LitCovid-sample-CHEBI","denotations":[{"id":"T4","span":{"begin":117,"end":130},"obj":"Chemical"},{"id":"T5","span":{"begin":182,"end":194},"obj":"Chemical"},{"id":"T6","span":{"begin":272,"end":279},"obj":"Chemical"},{"id":"T7","span":{"begin":302,"end":313},"obj":"Chemical"}],"attributes":[{"id":"A4","pred":"chebi_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/CHEBI_17089"},{"id":"A5","pred":"chebi_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/CHEBI_17089"},{"id":"A6","pred":"chebi_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/CHEBI_18154"},{"id":"A7","pred":"chebi_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_15841"}],"text":"e combined this information with bioinformatics analyses of natural variants and with existing 3D structures of both glycoproteins to generate molecular dynamics simulations of each glycoprotein both alone and interacting with one another. Our results highlight roles for glycans in sterically masking polypeptide epitopes and directly modulating Spike-ACE2 interactions. F"}
LitCovid-sample-sentences
{"project":"LitCovid-sample-sentences","denotations":[{"id":"T6","span":{"begin":240,"end":371},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"e combined this information with bioinformatics analyses of natural variants and with existing 3D structures of both glycoproteins to generate molecular dynamics simulations of each glycoprotein both alone and interacting with one another. Our results highlight roles for glycans in sterically masking polypeptide epitopes and directly modulating Spike-ACE2 interactions. F"}
LitCovid-sample-UniProt
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combined this information with bioinformatics analyses of natural variants and with existing 3D structures of both glycoproteins to generate molecular dynamics simulations of each glycoprotein both alone and interacting with one another. Our results highlight roles for glycans in sterically masking polypeptide epitopes and directly modulating Spike-ACE2 interactions. F"}
LitCovid-sample-PD-FMA
{"project":"LitCovid-sample-PD-FMA","denotations":[{"id":"T6","span":{"begin":117,"end":130},"obj":"Body_part"},{"id":"T7","span":{"begin":182,"end":194},"obj":"Body_part"}],"attributes":[{"id":"A6","pred":"fma_id","subj":"T6","obj":"http://purl.org/sig/ont/fma/fma62925"},{"id":"A7","pred":"fma_id","subj":"T7","obj":"http://purl.org/sig/ont/fma/fma62925"}],"text":"e combined this information with bioinformatics analyses of natural variants and with existing 3D structures of both glycoproteins to generate molecular dynamics simulations of each glycoprotein both alone and interacting with one another. Our results highlight roles for glycans in sterically masking polypeptide epitopes and directly modulating Spike-ACE2 interactions. F"}
LitCovid-PMC-OGER-BB
{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T15","span":{"begin":117,"end":130},"obj":"CHEBI:17089;BV_11;CHEBI:17089"},{"id":"T16","span":{"begin":182,"end":194},"obj":"CHEBI:17089;BV_11;CHEBI:17089"},{"id":"T17","span":{"begin":272,"end":279},"obj":"CHEBI:17089;CHEBI:17089"},{"id":"T18","span":{"begin":314,"end":322},"obj":"BV_9"},{"id":"T19","span":{"begin":336,"end":346},"obj":"GO:0065007"},{"id":"T20","span":{"begin":353,"end":357},"obj":"G_3;PG_10;PR:000003622"}],"text":"e combined this information with bioinformatics analyses of natural variants and with existing 3D structures of both glycoproteins to generate molecular dynamics simulations of each glycoprotein both alone and interacting with one another. Our results highlight roles for glycans in sterically masking polypeptide epitopes and directly modulating Spike-ACE2 interactions. F"}