(A). The spike proteins of the coronavirus are capable of binding to glycosaminoglycans (GAGs) on the ACE-2 receptor of the lung parenchyma, (B,C). An ex vivo LbL-nanocoated material acts as a decoy receptor for binding of the spike proteins and inactivating the virus. (D). Examples of objects that can be coated are disposable masks, gloves, shoes, catheters, clothing, and intubation tubes. More permanent implants such as vascular stents can also be coated. (All images of (D) were sampled under the Creative Commons License Attribution).