1. Introduction In this paper, the role of a layer-by-layer nanocoating approach to provide a mechanism of prevention of the spreading of the corona- and other viruses is described. The emphasis is placed on passive prevention techniques that may contribute to curbing the spread of the pathogen, rather than active pharmaceutical measures. It must be emphasized that the continued efforts toward vaccination and pharmacotherapeutic measures are essential and should continue. It is suggested that our non-pharmaceutical prophylaxis measures will aid the pharmaceutical measures in a complementary fashion. The perspective provided here is that several measures can be taken to prevent the spreading of the pathogen and attempt to combat the virus before it even enters the body. Despite our description of external measures against coronaviruses, it still relies significantly on the knowledge gained by renowned researchers who have established and studied vaccination and pharmacotherapeutic interventions against viruses in general.