To depict how the immune landscape changes with aging and SARS-CoV-2 infection, we enrolled young (YCO, n = 2) and aged (ACO, n = 2) patients with incipient COVID-19 (to assess the acute inflammatory state) in cohort-2 and young (YCR, n = 2) and aged (ACR, n = 2) patients who had recovered from COVID-19 (to assess the recovered state) in cohort-3.