At multivariable logistic regression analysis (Table 3), hypertension (P < 0.05) and known CAD (P < 0.001) were significantly associated with abnormal stress SPECT-MPI during both COVID-19 pandemic and the corresponding months of the previous 3 years. No significant interactions among risk factors were found. During the 2017–2019 period, also male gender (P < 0.001) and diabetes (P < 0.05) were associated with abnormal stress SPECT-MPI.
Table 3 Multivariable logistic regression analysis with abnormal MPI as dependent variable during COVID-19 emergency and during 2017–2019 3-year’s corresponding months
2020 2017–2019
β coefficient SE P value β coefficient SE P value
Age 0.005 0.023 0.834 − 0.004 0.007 0.60
Male gender 0.162 0.639 0.799 0.671 0.166 < .001
Body mass index − 0.013 0.049 0.785 − 0.024 0.014 0.08
Chest pain 0.542 0.508 0.286 − 0.264 0.149 0.08
Diabetes 0.565 0.466 0.225 0.310 0.148 < .05
Family history 0.180 0.454 0.692 − 0.163 0.150 0.28
Dyspnea 0.362 0.382 0.343 − 0.085 0.120 0.48
Hypertension − 1.573 0.709 < .05 0.376 0.196 < .05
Hyperlipidemia 0.822 0.621 0.186 − 0.239 0.167 0.15
Smoking 0.619 0.533 0.245 − 0.102 0.152 0.50
Known CAD 0.137 0.541 <.001 1.994 0.154 < .001
SE standard error, MPI myocardial perfusion imaging, CAD coronary artery disease