Characteristics of overall population are also described according to stress SPECT-MPI results during COVID-19 pandemic and during the corresponding months of 2017–2019 (Table 2). In both study periods, the percentage of patients with hyperlipidemia and known CAD was higher in patients with abnormal compared with those with normal stress SPECT-MPI findings, while during 2017–2019, patients with abnormal SPECT-MPI were older (P < 0.05) and had higher prevalence of diabetes (P < 0.005) and hypertension (P < 0.001). Table 2 Clinical characteristics of overall population according to MPI results during COVID-19 emergency and during 2017–2019 3-year’s corresponding months 2020 2017–2019 Normal (n = 79) Abnormal (n = 44) P value Normal (n = 820) Abnormal (n = 418) P value Age (years) 64 ± 11 64 ± 8 0.77 63 ± 11 65 ± 11 < .05 Male gender, n (%) 23 (38) 6 (43) 0.05 337 (41) 73 (17) < .001 Body mass index (kg/m2) 28.9 ± 4.9 28.1 ± 4.4 0.38 29.1 ± 6.1 27.9 ± 4.2 < .001 Chest pain, n (%) 22 (38) 15 (43) 0.47 308 (38) 123 (29) < .005 Diabetes, n (%) 28 (19) 19 (36) 0.40 234 (29) 156 (37) < .005 Dyspnea, n (%) 29 (22) 20 (25) 0.34 375 (46) 200 (48) 0.48 Family history, n (%) 36 (48) 24 (41) 0.34 446 (54) 223 (53) 0.73 Hypertension, n (%) 66 (62) 36 (76) 0.81 614 (75) 354 (85) < .001 Hyperlipidemia, n (%) 54 (55) 38 (57) < .05 540 (66) 317 (76) < .001 Smoking, n (%) 15 (55) 11 (57) 0.43 258 (31) 132 (32) 0.97 Known CAD n (%) 21 (55) 31 (57) < .001 224 (27) 317 (76) < .001 Values are expressed as mean value ± standard deviation or as number (percentage) of subjects. MPI myocardial perfusion imaging, CAD coronary artery disease