It should be noted that the overall risk of a COVID-19 patient being treated with JAK inhibitors and afflicted with tuberculosis as a side effect is likely exceptionally low, especially given that for a COVID-19 patient, treatments for many of the trials are carried out for a couple of weeks. The risk of developing serious infections, such as tuberculosis, is higher for patients that are on medication causing chronic immunosuppression, such as would be the case for a patient with a chronic illness like rheumatologic disorders, or patients with latent tuberculosis. However, with a short course of treatment in the case of a COVID-19 patient, it is unclear whether the period of immunosuppression would be long enough to result in a meaningful risk. In addition, latent tuberculosis can be tested for rather quickly (1-2 days) with a T-spot. TB test. This would normally be carried out for patients treated with JAK inhibitors, although there may be more of a delay than is ideal for patients with high risk COVID-19.