PMC:7408073 / 78484-78709 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T451","span":{"begin":116,"end":121},"obj":"Body_part"}],"attributes":[{"id":"A451","pred":"fma_id","subj":"T451","obj":"http://purl.org/sig/ont/fma/fma9670"}],"text":"It can, therefore, be supposed that a basal hyperactivity of ACE2 and consequent ACE/ACE2 pathway disequilibrium in blood might predispose to the development of more severe COVID-19 symptoms that involve both arms of the RAS."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T150","span":{"begin":116,"end":121},"obj":"Body_part"},{"id":"T151","span":{"begin":221,"end":224},"obj":"Body_part"}],"attributes":[{"id":"A150","pred":"uberon_id","subj":"T150","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"A151","pred":"uberon_id","subj":"T151","obj":"http://purl.obolibrary.org/obo/UBERON_0018229"}],"text":"It can, therefore, be supposed that a basal hyperactivity of ACE2 and consequent ACE/ACE2 pathway disequilibrium in blood might predispose to the development of more severe COVID-19 symptoms that involve both arms of the RAS."}

{"project":"LitCovid-PubTator","denotations":[{"id":"2739","span":{"begin":61,"end":65},"obj":"Gene"},{"id":"2740","span":{"begin":81,"end":84},"obj":"Gene"},{"id":"2741","span":{"begin":85,"end":89},"obj":"Gene"},{"id":"2796","span":{"begin":44,"end":57},"obj":"Disease"},{"id":"2797","span":{"begin":173,"end":181},"obj":"Disease"}],"attributes":[{"id":"A2739","pred":"tao:has_database_id","subj":"2739","obj":"Gene:59272"},{"id":"A2740","pred":"tao:has_database_id","subj":"2740","obj":"Gene:59272"},{"id":"A2741","pred":"tao:has_database_id","subj":"2741","obj":"Gene:59272"},{"id":"A2796","pred":"tao:has_database_id","subj":"2796","obj":"MESH:D006948"},{"id":"A2797","pred":"tao:has_database_id","subj":"2797","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"It can, therefore, be supposed that a basal hyperactivity of ACE2 and consequent ACE/ACE2 pathway disequilibrium in blood might predispose to the development of more severe COVID-19 symptoms that involve both arms of the RAS."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T410","span":{"begin":173,"end":181},"obj":"Disease"}],"attributes":[{"id":"A410","pred":"mondo_id","subj":"T410","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"It can, therefore, be supposed that a basal hyperactivity of ACE2 and consequent ACE/ACE2 pathway disequilibrium in blood might predispose to the development of more severe COVID-19 symptoms that involve both arms of the RAS."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T949","span":{"begin":36,"end":37},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T950","span":{"begin":116,"end":121},"obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"T951","span":{"begin":116,"end":121},"obj":"http://www.ebi.ac.uk/efo/EFO_0000296"},{"id":"T952","span":{"begin":209,"end":213},"obj":"http://www.ebi.ac.uk/efo/EFO_0001410"}],"text":"It can, therefore, be supposed that a basal hyperactivity of ACE2 and consequent ACE/ACE2 pathway disequilibrium in blood might predispose to the development of more severe COVID-19 symptoms that involve both arms of the RAS."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T323","span":{"begin":221,"end":224},"obj":"Chemical"}],"attributes":[{"id":"A16316","pred":"chebi_id","subj":"T323","obj":"http://purl.obolibrary.org/obo/CHEBI_63620"}],"text":"It can, therefore, be supposed that a basal hyperactivity of ACE2 and consequent ACE/ACE2 pathway disequilibrium in blood might predispose to the development of more severe COVID-19 symptoms that involve both arms of the RAS."}

{"project":"LitCovid-sentences","denotations":[{"id":"T384","span":{"begin":0,"end":225},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"It can, therefore, be supposed that a basal hyperactivity of ACE2 and consequent ACE/ACE2 pathway disequilibrium in blood might predispose to the development of more severe COVID-19 symptoms that involve both arms of the RAS."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T122","span":{"begin":44,"end":57},"obj":"Phenotype"}],"attributes":[{"id":"A122","pred":"hp_id","subj":"T122","obj":"http://purl.obolibrary.org/obo/HP_0000752"}],"text":"It can, therefore, be supposed that a basal hyperactivity of ACE2 and consequent ACE/ACE2 pathway disequilibrium in blood might predispose to the development of more severe COVID-19 symptoms that involve both arms of the RAS."}