n shown that ACE2 expression level in bronchial epithelium obtained by brushing from asthmatic and normal subjects was similar, suggesting that respiratory epithelial cells of healthy subjects and asthmatic patients have similar ability to bind to SARS-CoV-2 through ACE2. Of note, ACE2 was also identified as the receptor for the novel spike protein of SARS-CoV-2 [13]. Although the role of ACE2 in the pathogenesis of SARS-CoV-2 and in inducing lung in