PMC:7408073 / 28262-28500 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"1235","span":{"begin":49,"end":55},"obj":"Gene"},{"id":"1236","span":{"begin":56,"end":60},"obj":"Gene"},{"id":"1237","span":{"begin":75,"end":79},"obj":"Gene"},{"id":"1238","span":{"begin":93,"end":98},"obj":"Gene"},{"id":"1239","span":{"begin":157,"end":161},"obj":"Gene"},{"id":"1266","span":{"begin":15,"end":23},"obj":"Species"},{"id":"1267","span":{"begin":30,"end":33},"obj":"Species"},{"id":"1274","span":{"begin":25,"end":29},"obj":"Species"}],"attributes":[{"id":"A1235","pred":"tao:has_database_id","subj":"1235","obj":"Gene:6868"},{"id":"A1236","pred":"tao:has_database_id","subj":"1236","obj":"Gene:6868"},{"id":"A1237","pred":"tao:has_database_id","subj":"1237","obj":"Gene:59272"},{"id":"A1238","pred":"tao:has_database_id","subj":"1238","obj":"Gene:7124"},{"id":"A1239","pred":"tao:has_database_id","subj":"1239","obj":"Gene:59272"},{"id":"A1266","pred":"tao:has_database_id","subj":"1266","obj":"Tax:694009"},{"id":"A1267","pred":"tao:has_database_id","subj":"1267","obj":"Tax:11118"},{"id":"A1274","pred":"tao:has_database_id","subj":"1274","obj":"Tax:277944"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"In contrast to SARS-CoV, NL63-CoV did not induce ADAM17/TACE-mediated both ACE2 shedding and TNF-α secretion [17], suggesting that increased cleavability of ACE2 receptor and possibly of S1-S2 boundary may be crucial for disease severity."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T186","span":{"begin":15,"end":23},"obj":"Disease"},{"id":"T187","span":{"begin":15,"end":19},"obj":"Disease"}],"attributes":[{"id":"A186","pred":"mondo_id","subj":"T186","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A187","pred":"mondo_id","subj":"T187","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"In contrast to SARS-CoV, NL63-CoV did not induce ADAM17/TACE-mediated both ACE2 shedding and TNF-α secretion [17], suggesting that increased cleavability of ACE2 receptor and possibly of S1-S2 boundary may be crucial for disease severity."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T349","span":{"begin":187,"end":189},"obj":"http://purl.obolibrary.org/obo/CLO_0050050"},{"id":"T350","span":{"begin":190,"end":192},"obj":"http://purl.obolibrary.org/obo/CLO_0008922"},{"id":"T351","span":{"begin":190,"end":192},"obj":"http://purl.obolibrary.org/obo/CLO_0050052"}],"text":"In contrast to SARS-CoV, NL63-CoV did not induce ADAM17/TACE-mediated both ACE2 shedding and TNF-α secretion [17], suggesting that increased cleavability of ACE2 receptor and possibly of S1-S2 boundary may be crucial for disease severity."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T244","span":{"begin":190,"end":192},"obj":"Chemical"}],"attributes":[{"id":"A244","pred":"chebi_id","subj":"T244","obj":"http://purl.obolibrary.org/obo/CHEBI_29387"}],"text":"In contrast to SARS-CoV, NL63-CoV did not induce ADAM17/TACE-mediated both ACE2 shedding and TNF-α secretion [17], suggesting that increased cleavability of ACE2 receptor and possibly of S1-S2 boundary may be crucial for disease severity."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T50","span":{"begin":99,"end":108},"obj":"http://purl.obolibrary.org/obo/GO_0046903"}],"text":"In contrast to SARS-CoV, NL63-CoV did not induce ADAM17/TACE-mediated both ACE2 shedding and TNF-α secretion [17], suggesting that increased cleavability of ACE2 receptor and possibly of S1-S2 boundary may be crucial for disease severity."}

{"project":"LitCovid-sentences","denotations":[{"id":"T133","span":{"begin":0,"end":238},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"In contrast to SARS-CoV, NL63-CoV did not induce ADAM17/TACE-mediated both ACE2 shedding and TNF-α secretion [17], suggesting that increased cleavability of ACE2 receptor and possibly of S1-S2 boundary may be crucial for disease severity."}

{"project":"2_test","denotations":[{"id":"32708755-18490652-20678742","span":{"begin":110,"end":112},"obj":"18490652"}],"text":"In contrast to SARS-CoV, NL63-CoV did not induce ADAM17/TACE-mediated both ACE2 shedding and TNF-α secretion [17], suggesting that increased cleavability of ACE2 receptor and possibly of S1-S2 boundary may be crucial for disease severity."}