PMC:7408073 / 26140-26483
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T182 | 278-285 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1027 | 11-19 | Gene | denotes | Ang (1–7 | Gene:305843 |
| 1028 | 61-67 | Gene | denotes | Ang II | Gene:24179 |
| 1029 | 77-81 | Gene | denotes | ACE2 | Gene:302668 |
| 1030 | 166-170 | Gene | denotes | ACE2 | Gene:302668 |
| 1031 | 219-227 | Gene | denotes | Ang (1–7 | Gene:305843 |
| 1032 | 249-253 | Gene | denotes | ACE2 | Gene:302668 |
| 1060 | 141-147 | Gene | denotes | Ang II | Gene:24179 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T330 | 112-119 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
| T331 | 269-277 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T332 | 334-342 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T219 | 11-14 | Chemical | denotes | Ang | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T220 | 33-38 | Chemical | denotes | ACEIs | http://purl.obolibrary.org/obo/CHEBI_35457 |
| T221 | 61-64 | Chemical | denotes | Ang | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T222 | 65-67 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
| T223 | 108-111 | Chemical | denotes | Ang | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T224 | 112-119 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T225 | 141-144 | Chemical | denotes | Ang | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T226 | 145-147 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
| T227 | 219-222 | Chemical | denotes | Ang | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T228 | 278-285 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T47 | 254-267 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | transcription |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T122 | 0-343 | Sentence | denotes | Therefore, Ang (1–7) (as well as ACEIs and ARBs), preventing Ang II-mediated ACE2 downregulation, shift the Ang peptide balance in favour of Ang II metabolisation by ACE2, which, in turn, leads to further production of Ang (1–7), finally sustaining ACE2 transcription, membrane protein expression and eventually shedding and systemic activity. |