PMC:7408073 / 18658-19024 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T124","span":{"begin":50,"end":66},"obj":"Body_part"},{"id":"T125","span":{"begin":67,"end":86},"obj":"Body_part"},{"id":"T126","span":{"begin":81,"end":86},"obj":"Body_part"},{"id":"T127","span":{"begin":135,"end":139},"obj":"Body_part"},{"id":"T128","span":{"begin":144,"end":151},"obj":"Body_part"},{"id":"T129","span":{"begin":334,"end":345},"obj":"Body_part"},{"id":"T130","span":{"begin":357,"end":363},"obj":"Body_part"}],"attributes":[{"id":"A124","pred":"fma_id","subj":"T124","obj":"http://purl.org/sig/ont/fma/fma66326"},{"id":"A125","pred":"fma_id","subj":"T125","obj":"http://purl.org/sig/ont/fma/fma14072"},{"id":"A126","pred":"fma_id","subj":"T126","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A127","pred":"fma_id","subj":"T127","obj":"http://purl.org/sig/ont/fma/fma67122"},{"id":"A128","pred":"fma_id","subj":"T128","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A129","pred":"fma_id","subj":"T129","obj":"http://purl.org/sig/ont/fma/fma63916"},{"id":"A130","pred":"fma_id","subj":"T130","obj":"http://purl.org/sig/ont/fma/fma32558"}],"text":"ia [57]. Moreover, under hypoxic conditions human pulmonary artery smooth muscle cells upregulated both (arms of the RAS) ACE and ACE2 mRNA and protein expression, and ACE2 was subsequently downregulated by (ACE-derived) Ang II through an AT1R-mediated process [58]. Similarly, both ACE and ACE2 expression were increased in vascular endothelium and smooth muscle of"}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T36","span":{"begin":50,"end":66},"obj":"Body_part"},{"id":"T37","span":{"begin":60,"end":66},"obj":"Body_part"},{"id":"T38","span":{"begin":117,"end":120},"obj":"Body_part"},{"id":"T39","span":{"begin":334,"end":345},"obj":"Body_part"}],"attributes":[{"id":"A36","pred":"uberon_id","subj":"T36","obj":"http://purl.obolibrary.org/obo/UBERON_0002012"},{"id":"A37","pred":"uberon_id","subj":"T37","obj":"http://purl.obolibrary.org/obo/UBERON_0001637"},{"id":"A38","pred":"uberon_id","subj":"T38","obj":"http://purl.obolibrary.org/obo/UBERON_0018229"},{"id":"A39","pred":"uberon_id","subj":"T39","obj":"http://purl.obolibrary.org/obo/UBERON_0001986"}],"text":"ia [57]. Moreover, under hypoxic conditions human pulmonary artery smooth muscle cells upregulated both (arms of the RAS) ACE and ACE2 mRNA and protein expression, and ACE2 was subsequently downregulated by (ACE-derived) Ang II through an AT1R-mediated process [58]. Similarly, both ACE and ACE2 expression were increased in vascular endothelium and smooth muscle of"}

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{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T122","span":{"begin":117,"end":120},"obj":"Chemical"},{"id":"T123","span":{"begin":144,"end":151},"obj":"Chemical"},{"id":"T124","span":{"begin":221,"end":224},"obj":"Chemical"},{"id":"T125","span":{"begin":225,"end":227},"obj":"Chemical"}],"attributes":[{"id":"A122","pred":"chebi_id","subj":"T122","obj":"http://purl.obolibrary.org/obo/CHEBI_63620"},{"id":"A123","pred":"chebi_id","subj":"T123","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A124","pred":"chebi_id","subj":"T124","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"},{"id":"A125","pred":"chebi_id","subj":"T125","obj":"http://purl.obolibrary.org/obo/CHEBI_74067"}],"text":"ia [57]. Moreover, under hypoxic conditions human pulmonary artery smooth muscle cells upregulated both (arms of the RAS) ACE and ACE2 mRNA and protein expression, and ACE2 was subsequently downregulated by (ACE-derived) Ang II through an AT1R-mediated process [58]. Similarly, both ACE and ACE2 expression were increased in vascular endothelium and smooth muscle of"}

{"project":"LitCovid-sentences","denotations":[{"id":"T92","span":{"begin":9,"end":266},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"ia [57]. Moreover, under hypoxic conditions human pulmonary artery smooth muscle cells upregulated both (arms of the RAS) ACE and ACE2 mRNA and protein expression, and ACE2 was subsequently downregulated by (ACE-derived) Ang II through an AT1R-mediated process [58]. Similarly, both ACE and ACE2 expression were increased in vascular endothelium and smooth muscle of"}

{"project":"2_test","denotations":[{"id":"32708755-30989646-20678711","span":{"begin":4,"end":6},"obj":"30989646"}],"text":"ia [57]. Moreover, under hypoxic conditions human pulmonary artery smooth muscle cells upregulated both (arms of the RAS) ACE and ACE2 mRNA and protein expression, and ACE2 was subsequently downregulated by (ACE-derived) Ang II through an AT1R-mediated process [58]. Similarly, both ACE and ACE2 expression were increased in vascular endothelium and smooth muscle of"}