PMC:7402624 / 2136-2813
Annnotations
LitCovid-PD-FMA-UBERON
{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T10","span":{"begin":23,"end":27},"obj":"Body_part"},{"id":"T11","span":{"begin":64,"end":68},"obj":"Body_part"},{"id":"T12","span":{"begin":106,"end":110},"obj":"Body_part"},{"id":"T13","span":{"begin":303,"end":306},"obj":"Body_part"},{"id":"T14","span":{"begin":323,"end":328},"obj":"Body_part"},{"id":"T15","span":{"begin":336,"end":341},"obj":"Body_part"},{"id":"T16","span":{"begin":395,"end":413},"obj":"Body_part"},{"id":"T17","span":{"begin":408,"end":413},"obj":"Body_part"},{"id":"T18","span":{"begin":429,"end":434},"obj":"Body_part"},{"id":"T19","span":{"begin":445,"end":449},"obj":"Body_part"},{"id":"T20","span":{"begin":530,"end":535},"obj":"Body_part"},{"id":"T21","span":{"begin":633,"end":637},"obj":"Body_part"}],"attributes":[{"id":"A10","pred":"fma_id","subj":"T10","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A11","pred":"fma_id","subj":"T11","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A12","pred":"fma_id","subj":"T12","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A13","pred":"fma_id","subj":"T13","obj":"http://purl.org/sig/ont/fma/fma20935"},{"id":"A14","pred":"fma_id","subj":"T14","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A15","pred":"fma_id","subj":"T15","obj":"http://purl.org/sig/ont/fma/fma9670"},{"id":"A16","pred":"fma_id","subj":"T16","obj":"http://purl.org/sig/ont/fma/fma84070"},{"id":"A17","pred":"fma_id","subj":"T17","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A18","pred":"fma_id","subj":"T18","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A19","pred":"fma_id","subj":"T19","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A20","pred":"fma_id","subj":"T20","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A21","pred":"fma_id","subj":"T21","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"f virus-specific CD4 T cell responses than virus-specific CD8 T cell responses, though pre-existing CD4 T cell responses to other coronaviruses also are found in a subset of subjects in the absence of SARS-CoV2 exposure (6). Inflammatory responses have been reported, including increases in IL-6- or GM-CSF-producing CD4 T cells in the blood (7) or decreases in immunoregulatory subsets such as regulatory T cells (Treg) or ɣδ T cells (8–11). T cell exhaustion (12, 13) or increased inhibitory receptor expression on peripheral T cells has also been reported (7, 14), though these inhibitory receptors are also increased following T cell activation (15). Moreover, although the"}
LitCovid-PD-UBERON
{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T1","span":{"begin":336,"end":341},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"uberon_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"}],"text":"f virus-specific CD4 T cell responses than virus-specific CD8 T cell responses, though pre-existing CD4 T cell responses to other coronaviruses also are found in a subset of subjects in the absence of SARS-CoV2 exposure (6). Inflammatory responses have been reported, including increases in IL-6- or GM-CSF-producing CD4 T cells in the blood (7) or decreases in immunoregulatory subsets such as regulatory T cells (Treg) or ɣδ T cells (8–11). T cell exhaustion (12, 13) or increased inhibitory receptor expression on peripheral T cells has also been reported (7, 14), though these inhibitory receptors are also increased following T cell activation (15). Moreover, although the"}
LitCovid-PubTator
{"project":"LitCovid-PubTator","denotations":[{"id":"63","span":{"begin":17,"end":20},"obj":"Gene"},{"id":"64","span":{"begin":100,"end":103},"obj":"Gene"},{"id":"65","span":{"begin":291,"end":295},"obj":"Gene"},{"id":"66","span":{"begin":300,"end":306},"obj":"Gene"},{"id":"67","span":{"begin":317,"end":320},"obj":"Gene"},{"id":"68","span":{"begin":58,"end":61},"obj":"Gene"},{"id":"69","span":{"begin":130,"end":143},"obj":"Species"},{"id":"70","span":{"begin":201,"end":210},"obj":"Species"}],"attributes":[{"id":"A63","pred":"tao:has_database_id","subj":"63","obj":"Gene:920"},{"id":"A64","pred":"tao:has_database_id","subj":"64","obj":"Gene:920"},{"id":"A65","pred":"tao:has_database_id","subj":"65","obj":"Gene:3569"},{"id":"A66","pred":"tao:has_database_id","subj":"66","obj":"Gene:1437"},{"id":"A67","pred":"tao:has_database_id","subj":"67","obj":"Gene:920"},{"id":"A68","pred":"tao:has_database_id","subj":"68","obj":"Gene:925"},{"id":"A69","pred":"tao:has_database_id","subj":"69","obj":"Tax:11118"},{"id":"A70","pred":"tao:has_database_id","subj":"70","obj":"Tax:2697049"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"f virus-specific CD4 T cell responses than virus-specific CD8 T cell responses, though pre-existing CD4 T cell responses to other coronaviruses also are found in a subset of subjects in the absence of SARS-CoV2 exposure (6). Inflammatory responses have been reported, including increases in IL-6- or GM-CSF-producing CD4 T cells in the blood (7) or decreases in immunoregulatory subsets such as regulatory T cells (Treg) or ɣδ T cells (8–11). T cell exhaustion (12, 13) or increased inhibitory receptor expression on peripheral T cells has also been reported (7, 14), though these inhibitory receptors are also increased following T cell activation (15). Moreover, although the"}
LitCovid-PD-MONDO
{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T20","span":{"begin":201,"end":205},"obj":"Disease"}],"attributes":[{"id":"A20","pred":"mondo_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"f virus-specific CD4 T cell responses than virus-specific CD8 T cell responses, though pre-existing CD4 T cell responses to other coronaviruses also are found in a subset of subjects in the absence of SARS-CoV2 exposure (6). Inflammatory responses have been reported, including increases in IL-6- or GM-CSF-producing CD4 T cells in the blood (7) or decreases in immunoregulatory subsets such as regulatory T cells (Treg) or ɣδ T cells (8–11). T cell exhaustion (12, 13) or increased inhibitory receptor expression on peripheral T cells has also been reported (7, 14), though these inhibitory receptors are also increased following T cell activation (15). Moreover, although the"}
LitCovid-PD-CLO
{"project":"LitCovid-PD-CLO","denotations":[{"id":"T18","span":{"begin":2,"end":7},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T19","span":{"begin":17,"end":20},"obj":"http://purl.obolibrary.org/obo/PR_000001004"},{"id":"T20","span":{"begin":21,"end":27},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T21","span":{"begin":43,"end":48},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T22","span":{"begin":58,"end":61},"obj":"http://purl.obolibrary.org/obo/CLO_0053438"},{"id":"T23","span":{"begin":62,"end":68},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T24","span":{"begin":100,"end":103},"obj":"http://purl.obolibrary.org/obo/PR_000001004"},{"id":"T25","span":{"begin":104,"end":110},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T26","span":{"begin":162,"end":163},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T27","span":{"begin":317,"end":320},"obj":"http://purl.obolibrary.org/obo/PR_000001004"},{"id":"T28","span":{"begin":321,"end":328},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T29","span":{"begin":336,"end":341},"obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"T30","span":{"begin":336,"end":341},"obj":"http://www.ebi.ac.uk/efo/EFO_0000296"},{"id":"T31","span":{"begin":395,"end":413},"obj":"http://purl.obolibrary.org/obo/CL_0000815"},{"id":"T32","span":{"begin":415,"end":419},"obj":"http://purl.obolibrary.org/obo/CL_0000792"},{"id":"T33","span":{"begin":427,"end":434},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T34","span":{"begin":438,"end":440},"obj":"http://purl.obolibrary.org/obo/CLO_0053733"},{"id":"T35","span":{"begin":443,"end":449},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T36","span":{"begin":528,"end":535},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T37","span":{"begin":536,"end":539},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T38","span":{"begin":631,"end":637},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T39","span":{"begin":638,"end":648},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"f virus-specific CD4 T cell responses than virus-specific CD8 T cell responses, though pre-existing CD4 T cell responses to other coronaviruses also are found in a subset of subjects in the absence of SARS-CoV2 exposure (6). Inflammatory responses have been reported, including increases in IL-6- or GM-CSF-producing CD4 T cells in the blood (7) or decreases in immunoregulatory subsets such as regulatory T cells (Treg) or ɣδ T cells (8–11). T cell exhaustion (12, 13) or increased inhibitory receptor expression on peripheral T cells has also been reported (7, 14), though these inhibitory receptors are also increased following T cell activation (15). Moreover, although the"}
LitCovid-PD-CHEBI
{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T5","span":{"begin":291,"end":293},"obj":"Chemical"},{"id":"T7","span":{"begin":300,"end":302},"obj":"Chemical"}],"attributes":[{"id":"A5","pred":"chebi_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A6","pred":"chebi_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A7","pred":"chebi_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_74120"}],"text":"f virus-specific CD4 T cell responses than virus-specific CD8 T cell responses, though pre-existing CD4 T cell responses to other coronaviruses also are found in a subset of subjects in the absence of SARS-CoV2 exposure (6). Inflammatory responses have been reported, including increases in IL-6- or GM-CSF-producing CD4 T cells in the blood (7) or decreases in immunoregulatory subsets such as regulatory T cells (Treg) or ɣδ T cells (8–11). T cell exhaustion (12, 13) or increased inhibitory receptor expression on peripheral T cells has also been reported (7, 14), though these inhibitory receptors are also increased following T cell activation (15). Moreover, although the"}
LitCovid-PD-GO-BP
{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T13","span":{"begin":225,"end":247},"obj":"http://purl.obolibrary.org/obo/GO_0006954"},{"id":"T14","span":{"begin":631,"end":648},"obj":"http://purl.obolibrary.org/obo/GO_0042110"},{"id":"T15","span":{"begin":633,"end":648},"obj":"http://purl.obolibrary.org/obo/GO_0001775"}],"text":"f virus-specific CD4 T cell responses than virus-specific CD8 T cell responses, though pre-existing CD4 T cell responses to other coronaviruses also are found in a subset of subjects in the absence of SARS-CoV2 exposure (6). Inflammatory responses have been reported, including increases in IL-6- or GM-CSF-producing CD4 T cells in the blood (7) or decreases in immunoregulatory subsets such as regulatory T cells (Treg) or ɣδ T cells (8–11). T cell exhaustion (12, 13) or increased inhibitory receptor expression on peripheral T cells has also been reported (7, 14), though these inhibitory receptors are also increased following T cell activation (15). Moreover, although the"}
LitCovid-sentences
{"project":"LitCovid-sentences","denotations":[{"id":"T19","span":{"begin":225,"end":442},"obj":"Sentence"},{"id":"T20","span":{"begin":443,"end":654},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"f virus-specific CD4 T cell responses than virus-specific CD8 T cell responses, though pre-existing CD4 T cell responses to other coronaviruses also are found in a subset of subjects in the absence of SARS-CoV2 exposure (6). Inflammatory responses have been reported, including increases in IL-6- or GM-CSF-producing CD4 T cells in the blood (7) or decreases in immunoregulatory subsets such as regulatory T cells (Treg) or ɣδ T cells (8–11). T cell exhaustion (12, 13) or increased inhibitory receptor expression on peripheral T cells has also been reported (7, 14), though these inhibitory receptors are also increased following T cell activation (15). Moreover, although the"}