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Together, these data highlight T cell activation in COVID-19 patients similar to what has been observed in other acute infections or vaccinations (37, 39, 40), but also identify patients with high, low, or essentially no T cell response based on KI67+ or CD38+HLA-DR+ compared to control subjects.\nFig. 3 CD4 T cell activation in a subset of COVID-19 patients associates with distinct CD4 T cell subsets.\n(A) Representative flow cytometry plots of the 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