Inhibits LPS and epithelial barrier disorder, stipulate expression of proinflammatory cytokine of macrophage (Wang et al., 2012). Improve thymus coefficient, spleen coefficient, immunoglobulin G (IgG) level of the mice (Li et al., 2017). Regulates effect of the balance of CD4+ and CD8+ T lymphocytes, and reduction of IL-2, IL-10, IL-1β and TNF-α level (He et al., 2006; Zong et al., 2015). Improves serum NO level of rats, reduces concentration of 5-HT, and downregulates the level of plasma motilin and colonic somatostatin (Huang et al., 2016).