CPMs have played an important role in preventing and treating epidemic diseases in China because they are convenient to use, easily stored and cost-effective. The positive role of CPMs has been emphasized in the “Diagnosis and Treatment of COVID-19 (Trial Version 7)” and other therapeutic regimens. During the medical observation period and early stage of COVID-19, HXZQC, LHQWC, SFJDC, and JHQGG can be selected according to different clinical manifestations. At the same time, they can also promote immunity against the virus. For severe and critical disease, the choice shall be made according to different syndromes during clinical treatment. For viral infections combined with mild bacterial infections, XYPI and TRQI can be used; for high fever with disturbance of consciousness, AGNHP can be used; for systemic inflammatory response syndrome or multiple organ function failure, XBJI is recommended; SMI can be used for immunosuppression; and SFI can be used for shock. Furthermore, the reason that TCM works is not only because it inhibits the virus, but also because it might block infection, regulate the immune response, inhibit the inflammatory storm, and promote repair of the body. Moreover, the prevention and control measures of COVID-19 have fully reflected the ideology of “preventive treatment of disease”.