The treatment recommendations can be supported by the 2016 Update guideline by the Infectious Diseases Society of America that the therapeutic and alternative medication of candidiasis infection have been given more detailed guidance opinions [34]. Generally, patients who are suspected or confirmed with IC should be treated with echinocandin (caspofungin, micafungin, and anidulafungin), azoles (fluconazole, voriconazole, itraconazole), and Amphotericin B and its liposomes, what’s more, TDM for azoles should be used to optimize efficacy and limit toxicity.