A major problem of HIT is its overdiagnosis. Only around 50% of EIA+ sera have platelet-activating properties and, therefore, do not have true HIT.10 Antiphospholipid syndrome has been reported in COVID-19 patients,11 and these patients often test false positive with HIT serology.9 In the ICU setting, HIT explains about 1 out of 100 cases of thrombocytopenia.8 Critically ill patients have other plausible non-HIT mechanisms to explain their thrombocytopenia, including septicemia, consumptive coagulopathy in non-HIT-related pulmonary embolism, or catastrophic antiphospholipid syndrome.8