Characteristics Patient 1a Patient 2 Patient 3 Patient 4 Patient 5 Age in years 63 53 63 70 46 Sex Male Male Male Female Female Indication for anticoagulation DVT Acute coronary syndrome and atrial fibrillation DVT DVT Suspected PE Confirmed thrombosis via imaging Yes No Yes Yes No Days from initiation of heparin to drop in platelets 11 7 6 8 2 4T score 6 5 7 7 4 PF4 antibody (optical density) Positive (1.243) Positive (0.707) Positive (0.767) Positive (0.042) Positive (0.307) Serotonin release assay Positive Negative Negative Negative Negative Presence of DIC by ISTH criteria No No No Yes Yes