Conclusion
COVID-19 infection is a highly prothrombotic state, resulting from a dysregulation of the coagulation cascade. COVID-19 and HIT are both prothrombotic and can lead to thrombocytopenia. Both entities may be complicated by DIC. Given a considerable overlap, there is potential for devastating consequences, if a diagnosis of HIT is missed. As most patients with COVID-19 receive prophylactic heparin, and those with severe disease are likely to develop venous thromboembolism and thrombocytopenia, unrelated to HIT, there could be an even greater potential for overdiagnosis of HIT.