Graphene has also been used as antiviral material. Polysulfates and fatty amines were grafted onto graphene surface via triazine chemistry for the treatment of herpes simplex virus.87 This strategy promotes the synergy between the electrostatic and hydrophobic interactions, showing incredibly high inhibition efficacy. Overall, graphene materials have shown a good capacity to block host cell viral entry. Disinfection with graphene family materials is also promising, offering the possibility to couple high viral binding with phototreatments. Regarding the GO and rGO activity in cellular environments, different parameters must be considered such as protein coronation, blood circulation time, and activity in vivo. So far, the use of sulfonic groups introduced via diazonium salt decomposition has been largely privileged. We take this opportunity to encourage future studies using other targeting groups (e.g., boronic acids) and grafting methods (e.g., epoxide ring opening or hydroxyl esterification reactions).