than 90% in the S2 subunit suggests that the fusion mechanism during virus infection is well-conserved [14,15].
While SARS-CoV-2 shares higher whole-genome sequence identity with bat-SL-CoVZC45 and bat-SL-CoVZXC21 (88–89%) than with SARS-CoV-1 (79–82%), the RBD of SARS-CoV-2 is more similar to SARS-CoV-1 RBD [8,9]. In line with this, several research groups have demonstrated that