Table Pairwise amino-acid identity across relevant coronaviruses in the sequence fragment of the spike glycoprotein S2 subunit recognised by monoclonal antibody 1A9 or the sequence of the full spike glycoprotein Query/reference Pairwise amino-acid identity (%) SARS-CoV-2 BatRaTG13 SARS-CoV-1 MERS OC43 HKU1 229E NL63 Fragment region of spike S2 SARS-Co-V2 100.00 SB SB SB SB SB SB SB BatRaTG13 99.40 100.00 SB SB SB SB SB SB SARS 93.10 92.50 100.00 SB SB SB SB SB MERS 39.00 39.00 39.00 100.00 SB SB SB SB OC43 39.00 39.00 38.40 51.20 100.00 SB SB SB HKU1 32.70 32.70 30.80 50.60 68.40 100.00 SB SB 229E 30.80 30.20 32.10 31.50 29.70 30.40 100.00 SB NL63 30.80 30.20 30.20 32.10 31.60 33.50 64.20 100.00 Full spike protein SARS-CoV-2 100.00 SB SB SB SB SB SB SB BatRaTG13 97.70 100.00 SB SB SB SB SB SB SARS-CoV-1 77.80 78.20 100.00 SB SB SB SB SB MERS 35.40 35.40 35.20 100.00 SB SB SB SB OC43 37.30 37.10 36.90 39.50 100.00 SB SB SB HKU1 35.20 35.30 35.00 39.00 67.00 100.00 SB SB 229E 41.70 41.50 41.80 41.80 43.50 43.50 100.00 SB NL63 36.30 36.20 36.20 35.40 39.70 37.80 64.70 100.00 MERS: Middle East respiratory syndrome; SARS-CoV-1: severe acute respiratory coronavirus; SARS-CoV-2: severe acute respiratory coronavirus; SB: shown below. High to low pairwise amino-acid identity are coloured coded respectively by contrasting green to red backgrounds. The sequence identity is not affected by the order in which paired sequences are compared so only one-way comparisons are shown to avoid redundancies; the abbreviation ‘SB’ is used when the pairwise amino-acid identity in question is already shown in a further cell of the table.