In the pancreas, ACE2 is expressed in different cell types including acinar cells and ductal cells (Figure 2—figure supplement 12). DPP4 is robustly expressed in pancreatic alpha cells with lower expression detected in ~20% of ductal cells, while TMPRSS2 and ANPEP are both strongly expressed in the acinar and ductal populations (Figure 2—figure supplement 12). These patterns are largely consistent with our observations of protein expression by IHC (Figure 2—figure supplement 11).