In the liver, expression of these genes was generally consistent with the protein expression patterns observed by IHC (Figure 2—figure supplement 11). ACE2 shows minimal detection throughout liver populations, while both DPP4 and ANPEP are expressed in the epithelial compartment (Figure 2—figure supplement 12). ANPEP expression is particularly high in the EPCAM+ population of cells which may mark hepatic progenitor cells. TMPRSS2 is also expressed in these cells and in a subset of mature hepatocytes, which is discordant with the lack of TMPRSS2 staining in the liver by IHC (Figure 2—figure supplement 12).