Our analyses of bulk RNA-seq, proteomics, and IHC demonstrated that all coronavirus receptors are highly expressed in the kidney in addition to the small intestine (Figure 2—figure supplements 2,6). scRNAseq of human and murine kidney corroborates this finding, showing that ACE2, DPP4, and ANPEP are each robustly expressed in epithelial cells of the proximal tubules (Figure 2—figure supplement 5). Although clinical data suggests that SARS-CoV-2 does not reside in the urine (Wang et al., 2020c), we wondered whether ACE2, DPP4, and ANPEP show an overlapping pattern of expression heterogeneity among proximal tubular cells similar to that observed among small intestinal enterocytes. To address this, we computed cosine similarity scores between gene expression vectors specifically among ~27,000 recovered human proximal tubule epithelial cells (Stewart et al., 2019) and found that again DPP4 and ANPEP are among the genes with the most similar expression profiles to ACE2 (Figure 2—figure supplement 3). This is further supported by the strong transcriptional correlations among GTEx kidney samples (n = 85) by bulk RNA-seq, where DPP4 and ANPEP are again among the top 1% of gene correlations to ACE2 among the ~16,600 genes with mean expression >1 TPM (Figure 2—figure supplement 6). These observations are quite consistent with our previous analysis of small intestinal data and together may suggest an underlying transcriptional network which coordinates the expression of coronavirus entry receptors across diverse human tissues and cell types.