ulum (ER) and transported to the Golgi. The viral RNA–N complex and S, M, and E proteins are further assembled in the ER–Golgi intermediate compartment (ERGIC) to form a mature virion, then released from host cells [62]. Natural products of HS and the allied polysaccharide, heparin, are involved and prevent infection by a range of viruses including S-associated coronavirus strain HSR1 [66]. HS is known to bind CoV surface proteins