Table 4  BioProject data analysis for differential gene expression between non-treated and SARS-CoV-2-treated NEHB and A549 cells.
WikiPathways   p-Adj
Photodynamic therapy-induced NF-kB survival signaling  0
IL-18 signaling pathway  8.6 × 10−9
miRNAs involvement in the immune response in sepsis  2.4 × 10−8
Cytokines and Inflammatory Response  9.9 × 10−7
Lung fibrosis  2.5 × 10−6
BioPlanet   p-Adj
Oncostatin M  0
Interleukin-1 regulation of extracellular matrix  0
Interleukin-5 regulation of apoptosis  0
TNF-alpha effects on cytokine activity, cell motility, and apoptosis  0
Immune system signaling by interferons, interleukins, prolactin, and growth hormones  0
KEGG   p-Adj
IL-17 signaling pathway  1.3 × 10−9
TNF signaling pathway  1.6 × 10−9
Legionellosis  3.5 × 10−9
Rheumatoid arthritis  5.4 × 10−9
Cytokine-cytokine receptor interaction  6.6 × 10−9
PANTHER   p-Adj
Plasminogen activating cascade  0.00156
Toll receptor signaling pathway  0.00911
CCKR signaling map ST  0.02550
Apoptosis signaling pathway  0.10282
Blood coagulation  0.10433
REACTOME   p-Adj
Interferon alpha/beta signaling  1.6 × 10−9
Interleukin-10 signaling  2.5 × 10−9
Interleukin-4 and Interleukin-13 signaling  2.4 × 10−7
Formation of the cornified envelope  1.3 × 10−5
Chemokine receptors bind chemokines  0.00047
Small Molecule Pathway DB   p-Adj
CD40L Signalling Pathway  0.25268
NF-kB Signaling Pathway  0.25268
Toll-Like Receptor Pathway 2  0.25268
Capecitabine Metabolism Pathway  0.25268
Capecitabine Action Pathway  0.25268
BIOCYC   p-Adj
vitamin D3 biosynthesis  0.03597
guanosine nucleotides degradation  0.03597
retinoate biosynthesis II  0.03597
guanosine nucleotides degradation III  0.03597
adenosine nucleotides degradation II  0.03597
Pathway Interaction DB   p-Adj
Validated transcriptional targets of AP1 family members Fra1 and Fra2  3.8 × 10−5
IL23-mediated signaling events  0.00050
CD40/CD40L signaling  0.02539
Glucocorticoid receptor regulatory network  0.02603
LPA receptor mediated events  0.04171