PMC:7352545 / 28686-32535
Annnotations
LitCovid_Glycan-Motif-Structure
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T103 | 170-172 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
T104 | 227-229 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
T105 | 299-301 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
T106 | 785-787 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
T107 | 805-807 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
T108 | 1003-1009 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | Neu5Ac |
T109 | 1063-1069 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | Neu5Ac |
T110 | 1114-1120 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | Neu5Ac |
T111 | 1203-1209 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | Neu5Ac |
T112 | 1267-1273 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | Neu5Ac |
T113 | 1341-1347 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | Neu5Ac |
T114 | 1480-1482 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
T115 | 1544-1546 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
T116 | 2252-2254 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
T117 | 2347-2349 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
T118 | 2618-2620 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
T119 | 2774-2776 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
T120 | 2837-2839 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
T121 | 3026-3028 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
T122 | 3088-3090 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
T123 | 3136-3142 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | Neu5Ac |
T124 | 3244-3246 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
T125 | 3272-3274 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
T126 | 3451-3453 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
T127 | 3498-3500 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
T128 | 3533-3535 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
T129 | 3747-3749 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
T130 | 3816-3818 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | SA |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T234 | 56-64 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
T235 | 185-192 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T236 | 251-266 | Body_part | denotes | red blood cells | http://purl.org/sig/ont/fma/fma62845 |
T237 | 261-266 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T238 | 358-365 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T239 | 419-431 | Body_part | denotes | carbohydrate | http://purl.org/sig/ont/fma/fma82737 |
T240 | 550-555 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T241 | 614-626 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
T242 | 660-672 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
T243 | 696-708 | Body_part | denotes | cell surface | http://purl.org/sig/ont/fma/fma67653 |
T244 | 696-700 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T245 | 717-724 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T246 | 856-878 | Body_part | denotes | cell adhesion molecule | http://purl.org/sig/ont/fma/fma67214 |
T247 | 856-860 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T248 | 972-976 | Body_part | denotes | gene | http://purl.org/sig/ont/fma/fma74402 |
T249 | 1704-1716 | Body_part | denotes | carbohydrate | http://purl.org/sig/ont/fma/fma82737 |
T250 | 1727-1735 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
T251 | 1949-1953 | Body_part | denotes | gene | http://purl.org/sig/ont/fma/fma74402 |
T252 | 2017-2021 | Body_part | denotes | gene | http://purl.org/sig/ont/fma/fma74402 |
T253 | 2904-2912 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
T254 | 3301-3314 | Body_part | denotes | glycoproteins | http://purl.org/sig/ont/fma/fma62925 |
T255 | 3411-3423 | Body_part | denotes | erythrocytes | http://purl.org/sig/ont/fma/fma62845 |
T256 | 3592-3604 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
T257 | 3655-3660 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T258 | 3712-3717 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T259 | 3800-3812 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
T260 | 3843-3848 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T6 | 255-260 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T112 | 735-744 | Disease | denotes | hepatitis | http://purl.obolibrary.org/obo/MONDO_0002251 |
T113 | 1845-1854 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
T114 | 2078-2087 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
T115 | 2963-2980 | Disease | denotes | encephalomyelitis | http://purl.obolibrary.org/obo/MONDO_0005156 |
T116 | 3667-3676 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T375 | 36-39 | http://purl.obolibrary.org/obo/CLO_0053120 | denotes | HEs |
T376 | 40-43 | http://purl.obolibrary.org/obo/CLO_0053120 | denotes | HEs |
T377 | 130-133 | http://purl.obolibrary.org/obo/CLO_0053120 | denotes | HEs |
T378 | 150-155 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T379 | 251-266 | http://purl.obolibrary.org/obo/CL_0000232 | denotes | red blood cells |
T380 | 286-288 | http://purl.obolibrary.org/obo/CLO_0001407 | denotes | 52 |
T381 | 417-418 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T382 | 518-523 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T383 | 538-541 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
T384 | 550-555 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T385 | 645-646 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T386 | 696-700 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T387 | 745-750 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T388 | 856-860 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T389 | 945-948 | http://purl.obolibrary.org/obo/CLO_0053120 | denotes | HEs |
T390 | 972-976 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | gene |
T391 | 1036-1039 | http://purl.obolibrary.org/obo/CLO_0053120 | denotes | HEs |
T392 | 1055-1057 | http://purl.obolibrary.org/obo/CLO_0037284 | denotes | C4 |
T393 | 1084-1089 | http://purl.obolibrary.org/obo/CLO_0007836 | denotes | mouse |
T394 | 1195-1197 | http://purl.obolibrary.org/obo/CLO_0037284 | denotes | C4 |
T395 | 1249-1251 | http://purl.obolibrary.org/obo/CLO_0002131 | denotes | C5 |
T396 | 1321-1325 | http://purl.obolibrary.org/obo/CLO_0053061 | denotes | a C5 |
T397 | 1333-1335 | http://purl.obolibrary.org/obo/CLO_0037284 | denotes | C4 |
T398 | 1419-1422 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
T399 | 1431-1434 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
T400 | 1471-1474 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
T401 | 1637-1638 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T402 | 1644-1645 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T403 | 1782-1789 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
T404 | 1855-1860 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T405 | 1928-1929 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T406 | 1949-1953 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | gene |
T407 | 1973-1974 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T408 | 1989-1990 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T409 | 2017-2021 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | gene |
T410 | 2036-2039 | http://purl.obolibrary.org/obo/CLO_0001618 | denotes | a 9 |
T411 | 2036-2039 | http://purl.obolibrary.org/obo/CLO_0001619 | denotes | a 9 |
T412 | 2036-2039 | http://purl.obolibrary.org/obo/CLO_0001620 | denotes | a 9 |
T413 | 2088-2093 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T414 | 2321-2326 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T415 | 2434-2437 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
T416 | 2453-2454 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T417 | 2494-2495 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T418 | 2524-2525 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T419 | 2592-2593 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T420 | 2709-2714 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T421 | 2861-2866 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T422 | 2981-2986 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T423 | 3084-3087 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T424 | 3186-3189 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
T425 | 3208-3211 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAs |
T426 | 3403-3410 | http://purl.obolibrary.org/obo/NCBITaxon_9031 | denotes | chicken |
T427 | 3411-3423 | http://purl.obolibrary.org/obo/CL_0000232 | denotes | erythrocytes |
T428 | 3463-3465 | http://purl.obolibrary.org/obo/CLO_0001407 | denotes | 52 |
T429 | 3556-3557 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T430 | 3655-3660 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T431 | 3712-3717 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T432 | 3843-3848 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T796 | 56-64 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
T797 | 170-172 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
T802 | 185-192 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T803 | 227-229 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
T808 | 299-301 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
T813 | 358-365 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T814 | 396-403 | Chemical | denotes | glycans | http://purl.obolibrary.org/obo/CHEBI_18154 |
T815 | 419-431 | Chemical | denotes | carbohydrate | http://purl.obolibrary.org/obo/CHEBI_16646 |
T816 | 572-574 | Chemical | denotes | HA | http://purl.obolibrary.org/obo/CHEBI_73924 |
T817 | 614-626 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
T818 | 647-649 | Chemical | denotes | HA | http://purl.obolibrary.org/obo/CHEBI_73924 |
T819 | 660-672 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
T820 | 717-724 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T821 | 785-787 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
T826 | 805-807 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
T831 | 848-855 | Chemical | denotes | antigen | http://purl.obolibrary.org/obo/CHEBI_59132 |
T832 | 870-878 | Chemical | denotes | molecule | http://purl.obolibrary.org/obo/CHEBI_25367 |
T833 | 1000-1002 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
T835 | 1003-1009 | Chemical | denotes | Neu5Ac | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_75133 |
T837 | 1060-1062 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
T839 | 1063-1069 | Chemical | denotes | Neu5Ac | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_75133 |
T841 | 1111-1113 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
T843 | 1114-1120 | Chemical | denotes | Neu5Ac | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_75133 |
T845 | 1200-1202 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
T847 | 1203-1209 | Chemical | denotes | Neu5Ac | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_75133 |
T849 | 1264-1266 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
T851 | 1267-1273 | Chemical | denotes | Neu5Ac | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_75133 |
T853 | 1338-1340 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
T855 | 1341-1347 | Chemical | denotes | Neu5Ac | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_75133 |
T857 | 1428-1430 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
T859 | 1442-1444 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
T860 | 1468-1470 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
T862 | 1480-1482 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
T867 | 1544-1546 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
T872 | 1704-1716 | Chemical | denotes | carbohydrate | http://purl.obolibrary.org/obo/CHEBI_16646 |
T873 | 1727-1735 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
T874 | 2042-2044 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
T876 | 2252-2254 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
T881 | 2266-2273 | Chemical | denotes | glycans | http://purl.obolibrary.org/obo/CHEBI_18154 |
T882 | 2347-2349 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
T887 | 2431-2433 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
T889 | 2615-2617 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
T891 | 2618-2620 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
T896 | 2715-2720 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
T897 | 2771-2773 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
T899 | 2774-2776 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
T904 | 2834-2836 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
T906 | 2837-2839 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
T911 | 2846-2848 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
T912 | 2867-2872 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
T913 | 2904-2912 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
T914 | 3026-3028 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
T919 | 3088-3090 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
T924 | 3136-3142 | Chemical | denotes | Neu5Ac | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_75133 |
T926 | 3183-3185 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
T928 | 3205-3207 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
T930 | 3244-3246 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
T935 | 3272-3274 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
T940 | 3301-3314 | Chemical | denotes | glycoproteins | http://purl.obolibrary.org/obo/CHEBI_17089 |
T941 | 3448-3450 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
T943 | 3451-3453 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
T948 | 3498-3500 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
T953 | 3530-3532 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
T955 | 3533-3535 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
T960 | 3592-3604 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
T961 | 3723-3725 | Chemical | denotes | NA | http://purl.obolibrary.org/obo/CHEBI_33696 |
T962 | 3747-3749 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
T967 | 3800-3812 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
T968 | 3816-3818 | Chemical | denotes | SA | http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801|http://purl.obolibrary.org/obo/CHEBI_26667 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T50 | 856-878 | http://purl.obolibrary.org/obo/GO_0098631 | denotes | cell adhesion molecule |
T51 | 856-869 | http://purl.obolibrary.org/obo/GO_0007155 | denotes | cell adhesion |
T52 | 3829-3842 | http://purl.obolibrary.org/obo/GO_0044409 | denotes | entry to host |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T283 | 0-4 | Sentence | denotes | 5.2. |
T284 | 5-39 | Sentence | denotes | Substrate Diversity of the CoV HEs |
T285 | 40-117 | Sentence | denotes | HEs as envelope proteins are found in CoVs, orthomyxoviruses and toroviruses. |
T286 | 118-181 | Sentence | denotes | Coronaviral HEs are involved in virus attachment to SA species. |
T287 | 182-290 | Sentence | denotes | HE protein in β-CoVs binds to Neu5,9Ac2 form SA and agglutinates the red blood cells (RBCs) of rodents [52]. |
T288 | 291-404 | Sentence | denotes | As with SA-O-acetylesterase, HE potentiates viral entry with the S protein and spreading via the mucosal glycans. |
T289 | 405-473 | Sentence | denotes | It contains a carbohydrate-recognizing domain (CRD) known in lectin. |
T290 | 474-556 | Sentence | denotes | The HE glycan-binding domain (GBD) mediates virus attachment to SAs on host cells. |
T291 | 557-575 | Sentence | denotes | HE is the only HA. |
T292 | 576-709 | Sentence | denotes | This indicates that compared to the S glycoprotein, HE is only minor a HA and the S glycoprotein mainly attaches to the cell surface. |
T293 | 710-932 | Sentence | denotes | The HE protein of murine hepatitis virus (MHV), an enveloped CoV, binds to SA-4-acetylester or SA-9-O-acetylester of the carcinoembryonic antigen cell adhesion molecule 1a (CEACAM; known as CD66a) as the key receptor [53]. |
T294 | 933-1010 | Sentence | denotes | Murine CoVs HEs acquired by horizontal gene transfer, bind to C9-O-Ac Neu5Ac. |
T295 | 1011-1070 | Sentence | denotes | However, some murine CoV HEs cannot bind to C4-O-Ac Neu5Ac. |
T296 | 1071-1221 | Sentence | denotes | The original mouse MHV HE binds to C9-O-Ac Neu5Ac, while the MHV S-strain HE evolutionarily acquired the ability to bind to C4-O-Ac Neu5Ac [12,53,54]. |
T297 | 1222-1373 | Sentence | denotes | In terms of structure, the C5 N- and C9 O-Ac Neu5Ac-accomodating hydrophobic pocket was shifted to a C5 N- and C4-O-Ac Neu5Ac-accomodating pocket [55]. |
T298 | 1374-1436 | Sentence | denotes | Type I HE is specific for the 9-O-acetylated SAs (9-O-Ac-SAs). |
T299 | 1437-1475 | Sentence | denotes | Type II HE is specific for 4-O-Ac-SAs. |
T300 | 1476-1600 | Sentence | denotes | The SA-binding shift indicates quasi-synchronous adaptations of the SA-recognition sites of the lectin and esterase domains. |
T301 | 1601-1736 | Sentence | denotes | Type I HE monomers of β-CoV lineage A have a bimodular enzyme–lectin domain similar to cellular glycan/carbohydrate-modifying proteins. |
T302 | 1737-1941 | Sentence | denotes | Originally, HE homologs are found in various viruses including toroviruses and orthomyxoviruses such as the influenza virus C/D and isavirus, as well as the exceptional case of β-CoV lineage A among CoVs. |
T303 | 1942-2098 | Sentence | denotes | The HE gene was transmitted to a β-CoV lineage A progenitor via horizontal gene transfer from a 9-O-Ac-Sia–recognizing HEF, as shown in influenza virus C/D. |
T304 | 2099-2274 | Sentence | denotes | HE acquisition and expansion occurred by cross-species transmission over HE evolution and this phenomenon reflects viral evolutionary adaptation to host SA-containing glycans. |
T305 | 2275-2387 | Sentence | denotes | Therefore, CoV HE receptor switching precedes virus evolution driven by SA-containing glycan diversity of hosts. |
T306 | 2388-2489 | Sentence | denotes | For instance, the BcoV HE prefers 7,9-di-O-Ac-SAs, which is also a target of the bovine torovirus HE. |
T307 | 2490-2633 | Sentence | denotes | For a more outstanding case, such a switching event occurred in the murine CoVs for the β-CoV lineage A type switch toward O-Ac-SA recognition. |
T308 | 2634-2878 | Sentence | denotes | In the HE specificity of murine CoVs, two different murine CoV subtypes of virus group exist with one subtype possessing the typical 9-O-Ac-SA (type I) attachment factor and the other exclusively 4-O-Ac-SA (type II) attachment virus group [56]. |
T309 | 2879-3068 | Sentence | denotes | The first coronaviral HE proteins identified were from the porcine hemagglutinating encephalomyelitis virus (PHEV), BCoV and HCoV-OC43, which bear SA-9-O-acetylesterases similar to HEF [8]. |
T310 | 3069-3154 | Sentence | denotes | Rat CoV (RCoV) has SA-4-O-acetylesterases, converting Neu4,5Ac2 to Neu5Ac [53,57,58]. |
T311 | 3155-3212 | Sentence | denotes | Some murine CoVs prefer 4-O-Ac-SAs and others 9-O-Ac-SAs. |
T312 | 3213-3294 | Sentence | denotes | HCoV-OC43 and BCoV prefer α2-6-SA 9-O-acetylation by their SA-O-acetyleseterases. |
T313 | 3295-3467 | Sentence | denotes | The S glycoproteins of BCoV and HCoV-OC43 are Neu5,9Ac2-recognizing lectins and agglutinate murine, rat and chicken erythrocytes due to the enriched 9-O-Ac-SA species [52]. |
T314 | 3468-3551 | Sentence | denotes | BCoV and HCoV-OC43 adapted to SA receptor determinants of 9-O-Ac-SA receptors [59]. |
T315 | 3552-3661 | Sentence | denotes | For a second receptor, the binding of S glycoprotein to Neu5,9Ac2 receptor is essential for entry into cells. |
T316 | 3662-3849 | Sentence | denotes | BCoV-infection is prevented by prior treatment of cells with NA enzyme or with viral SA-O-acetylesterases, blocking the roles of HE and S glycoprotein in SA-dependent entry to host cells. |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32604730-1920630-51943993 | 286-288 | 1920630 | denotes | 52 |
32604730-10233932-51943994 | 928-930 | 10233932 | denotes | 53 |
32604730-16575523-51943995 | 1211-1213 | 16575523 | denotes | 12 |
32604730-10233932-51943996 | 1214-1216 | 10233932 | denotes | 53 |
32604730-20538854-51943997 | 1217-1219 | 20538854 | denotes | 54 |
32604730-16306577-51943998 | 1369-1371 | 16306577 | denotes | 55 |
32604730-27185912-51943999 | 2874-2876 | 27185912 | denotes | 56 |
32604730-3380803-51944000 | 3065-3066 | 3380803 | denotes | 8 |
32604730-10233932-51944001 | 3144-3146 | 10233932 | denotes | 53 |
32604730-11807232-51944002 | 3147-3149 | 11807232 | denotes | 57 |
32604730-1920630-51944003 | 3463-3465 | 1920630 | denotes | 52 |
32604730-1321878-51944004 | 3547-3549 | 1321878 | denotes | 59 |
T60595 | 286-288 | 1920630 | denotes | 52 |
T4696 | 928-930 | 10233932 | denotes | 53 |
T80351 | 1211-1213 | 16575523 | denotes | 12 |
T34204 | 1214-1216 | 10233932 | denotes | 53 |
T1499 | 1217-1219 | 20538854 | denotes | 54 |
T25059 | 1369-1371 | 16306577 | denotes | 55 |
T81483 | 2874-2876 | 27185912 | denotes | 56 |
T74157 | 3065-3066 | 3380803 | denotes | 8 |
T77726 | 3144-3146 | 10233932 | denotes | 53 |
T52426 | 3147-3149 | 11807232 | denotes | 57 |
T22208 | 3463-3465 | 1920630 | denotes | 52 |
T60367 | 3547-3549 | 1321878 | denotes | 59 |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T9 | 735-744 | Phenotype | denotes | hepatitis | http://purl.obolibrary.org/obo/HP_0012115 |