To this day, our understanding of the true impact of Aspergillus co-infections remains frustratingly limited. Therefore, guidance on proper management of these high-risk procedures to prevent transmission and super spreading of SARS-CoV-2 is needed. The European Confederation of Medical Mycology initiated national multicenter studies aiming to explore the risk of fungal infections during COVID-19 [94] and is currently working on diagnostic and treatment algorithms. Key goals are to improve the outcome by avoiding misdiagnosis and by initiation of early and targeted antifungal treatment.