The CRP remained highly stable over the following days at around 200 mg/L with a range of 192–214. However, the patient needed increasing oxygenation with a non-rebreathing mask. Empirical treatment of a suspected bacterial superinfection was started with ceftriaxone i.v. 2000 mg q24h. Five days after admission, the maximum (15 L O2) oxygenation with the non-rebreathing mask became insufficient and the patient was admitted to the ICU for respiratory support and intensive monitoring.