PMC:7344504 / 13300-14158 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7344504","sourcedb":"PMC","sourceid":"7344504","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7344504","text":"The LFD is particularly interesting in the ICU due to its short turnaround time. It has demonstrated a higher sensitivity but lower specificity in BAL fluids compared to galactomannan [36] and β-d-glucan [37] in IPA-probable and proven immunocompromised patients. In the ICU setting, however, LFD is suggested to have a lower sensitivity but comparable specificity to galactomannan testing in BAL fluids [35,38]. Noteworthily, a negative predictive value of \u003e96% has been reported in the ICU setting [39]. We used the OLM lateral flow device (AspLFD) on sequential patient tracheal aspirates, yielding positive results on all samples confirming the positive galactomannan result. Although suitable for its negative predictive value or as an additional diagnostic measure, further evaluation of lateral flow technology in critically ill patients is warranted.","tracks":[{"project":"LitCovid-PubTator","denotations":[{"id":"354","span":{"begin":254,"end":262},"obj":"Species"},{"id":"355","span":{"begin":565,"end":572},"obj":"Species"},{"id":"356","span":{"begin":836,"end":844},"obj":"Species"},{"id":"357","span":{"begin":170,"end":183},"obj":"Chemical"},{"id":"358","span":{"begin":193,"end":203},"obj":"Chemical"},{"id":"359","span":{"begin":368,"end":381},"obj":"Chemical"},{"id":"360","span":{"begin":658,"end":671},"obj":"Chemical"},{"id":"361","span":{"begin":821,"end":835},"obj":"Disease"}],"attributes":[{"id":"A354","pred":"tao:has_database_id","subj":"354","obj":"Tax:9606"},{"id":"A355","pred":"tao:has_database_id","subj":"355","obj":"Tax:9606"},{"id":"A356","pred":"tao:has_database_id","subj":"356","obj":"Tax:9606"},{"id":"A357","pred":"tao:has_database_id","subj":"357","obj":"MESH:C012990"},{"id":"A359","pred":"tao:has_database_id","subj":"359","obj":"MESH:C012990"},{"id":"A360","pred":"tao:has_database_id","subj":"360","obj":"MESH:C012990"},{"id":"A361","pred":"tao:has_database_id","subj":"361","obj":"MESH:D016638"},{"subj":"354","pred":"source","obj":"LitCovid-PubTator"},{"subj":"355","pred":"source","obj":"LitCovid-PubTator"},{"subj":"356","pred":"source","obj":"LitCovid-PubTator"},{"subj":"357","pred":"source","obj":"LitCovid-PubTator"},{"subj":"358","pred":"source","obj":"LitCovid-PubTator"},{"subj":"359","pred":"source","obj":"LitCovid-PubTator"},{"subj":"360","pred":"source","obj":"LitCovid-PubTator"},{"subj":"361","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T96","span":{"begin":84,"end":87},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T97","span":{"begin":101,"end":102},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T98","span":{"begin":185,"end":187},"obj":"http://purl.obolibrary.org/obo/CLO_0001313"},{"id":"T99","span":{"begin":318,"end":319},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T100","span":{"begin":382,"end":389},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T101","span":{"begin":427,"end":428},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T102","span":{"begin":463,"end":466},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T103","span":{"begin":535,"end":541},"obj":"http://purl.obolibrary.org/obo/OBI_0000968"}],"attributes":[{"subj":"T96","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T97","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T98","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T99","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T100","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T101","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T102","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T103","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T104","span":{"begin":4,"end":7},"obj":"Chemical"},{"id":"T105","span":{"begin":147,"end":150},"obj":"Chemical"},{"id":"T106","span":{"begin":170,"end":183},"obj":"Chemical"},{"id":"T107","span":{"begin":197,"end":203},"obj":"Chemical"},{"id":"T108","span":{"begin":212,"end":215},"obj":"Chemical"},{"id":"T110","span":{"begin":293,"end":296},"obj":"Chemical"},{"id":"T111","span":{"begin":368,"end":381},"obj":"Chemical"},{"id":"T112","span":{"begin":393,"end":396},"obj":"Chemical"},{"id":"T113","span":{"begin":658,"end":671},"obj":"Chemical"}],"attributes":[{"id":"A104","pred":"chebi_id","subj":"T104","obj":"http://purl.obolibrary.org/obo/CHEBI_73571"},{"id":"A105","pred":"chebi_id","subj":"T105","obj":"http://purl.obolibrary.org/obo/CHEBI_64198"},{"id":"A106","pred":"chebi_id","subj":"T106","obj":"http://purl.obolibrary.org/obo/CHEBI_27680"},{"id":"A107","pred":"chebi_id","subj":"T107","obj":"http://purl.obolibrary.org/obo/CHEBI_37163"},{"id":"A108","pred":"chebi_id","subj":"T108","obj":"http://purl.obolibrary.org/obo/CHEBI_17824"},{"id":"A109","pred":"chebi_id","subj":"T108","obj":"http://purl.obolibrary.org/obo/CHEBI_30802"},{"id":"A110","pred":"chebi_id","subj":"T110","obj":"http://purl.obolibrary.org/obo/CHEBI_73571"},{"id":"A111","pred":"chebi_id","subj":"T111","obj":"http://purl.obolibrary.org/obo/CHEBI_27680"},{"id":"A112","pred":"chebi_id","subj":"T112","obj":"http://purl.obolibrary.org/obo/CHEBI_64198"},{"id":"A113","pred":"chebi_id","subj":"T113","obj":"http://purl.obolibrary.org/obo/CHEBI_27680"},{"subj":"T104","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T105","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T106","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T107","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T108","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T110","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T111","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T112","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T113","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-PD-GlycoEpitope","denotations":[{"id":"T6","span":{"begin":170,"end":183},"obj":"GlycoEpitope"},{"id":"T7","span":{"begin":368,"end":381},"obj":"GlycoEpitope"},{"id":"T8","span":{"begin":658,"end":671},"obj":"GlycoEpitope"}],"attributes":[{"id":"A6","pred":"glyco_epitope_db_id","subj":"T6","obj":"http://www.glycoepitope.jp/epitopes/EP0510"},{"id":"A7","pred":"glyco_epitope_db_id","subj":"T7","obj":"http://www.glycoepitope.jp/epitopes/EP0510"},{"id":"A8","pred":"glyco_epitope_db_id","subj":"T8","obj":"http://www.glycoepitope.jp/epitopes/EP0510"},{"subj":"T6","pred":"source","obj":"LitCovid-PD-GlycoEpitope"},{"subj":"T7","pred":"source","obj":"LitCovid-PD-GlycoEpitope"},{"subj":"T8","pred":"source","obj":"LitCovid-PD-GlycoEpitope"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T103","span":{"begin":0,"end":80},"obj":"Sentence"},{"id":"T104","span":{"begin":81,"end":263},"obj":"Sentence"},{"id":"T105","span":{"begin":264,"end":412},"obj":"Sentence"},{"id":"T106","span":{"begin":413,"end":505},"obj":"Sentence"},{"id":"T107","span":{"begin":506,"end":679},"obj":"Sentence"},{"id":"T108","span":{"begin":680,"end":858},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T103","pred":"source","obj":"LitCovid-sentences"},{"subj":"T104","pred":"source","obj":"LitCovid-sentences"},{"subj":"T105","pred":"source","obj":"LitCovid-sentences"},{"subj":"T106","pred":"source","obj":"LitCovid-sentences"},{"subj":"T107","pred":"source","obj":"LitCovid-sentences"},{"subj":"T108","pred":"source","obj":"LitCovid-sentences"}]},{"project":"LitCovid-PD-HP","denotations":[{"id":"T21","span":{"begin":212,"end":215},"obj":"Phenotype"}],"attributes":[{"id":"A21","pred":"hp_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/HP_0020103"},{"subj":"T21","pred":"source","obj":"LitCovid-PD-HP"}]},{"project":"2_test","denotations":[{"id":"32517166-25903568-60114412","span":{"begin":185,"end":187},"obj":"25903568"},{"id":"32517166-24671798-60114413","span":{"begin":205,"end":207},"obj":"24671798"},{"id":"32517166-30565352-60114414","span":{"begin":408,"end":410},"obj":"30565352"},{"id":"32517166-25927915-60114415","span":{"begin":501,"end":503},"obj":"25927915"}],"attributes":[{"subj":"32517166-25903568-60114412","pred":"source","obj":"2_test"},{"subj":"32517166-24671798-60114413","pred":"source","obj":"2_test"},{"subj":"32517166-30565352-60114414","pred":"source","obj":"2_test"},{"subj":"32517166-25927915-60114415","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PubTator","color":"#ec9398","default":true},{"id":"LitCovid-PD-CLO","color":"#93b2ec"},{"id":"LitCovid-PD-CHEBI","color":"#ccec93"},{"id":"LitCovid-PD-GlycoEpitope","color":"#ec93e7"},{"id":"LitCovid-sentences","color":"#93ecd7"},{"id":"LitCovid-PD-HP","color":"#ecbd93"},{"id":"2_test","color":"#a393ec"}]}]}}