A. penicillioides is a xerophilic species occurring in dry habitats and in house dust; it is responsible for human and animal allergies. Dry oxygen supplementation intended to prevent aerosolization could explain the infection caused by this pathogen 12 . To the best of our knowledge, this is the fourth clinical report on A. penicillioides clinical infection. The other three are classified as keratitis, disseminated disease in a child with cystic fibrosis, and central nervous system arteritis 13  ,  14  ,  15 . No information is available on the antifungal sensitivity of this species or the frequency of invasive disease.