COVID-19 is characterized by asymptomatic and/or mild flu-like symptoms; however, about 20% of patients may progress to pneumonia and sepsis, thus requiring intensive support 1 . Patients with acute respiratory distress syndrome due to viral infections, such as SARS-CoV-2, are prone to secondary complications, including aspergillosis 2 . Invasive aspergillosis is not uncommon in immunocompromised patients, and is a well-described complication in acute respiratory failure and severe influenza-related pneumonia 3 . A retrospective multicenter cohort study showed that influenza infection was an independent risk factor for invasive pulmonary aspergillosis (IPA) 4 .