Homeostasis of human cells is regulated by the secretion of the stress hormone glucocorticoid, to varying degrees, under different external stimuli. PD has been the most effective and safer drug for HP for a long time. It can strongly suppress several cytokines, such as IL-1, IL-6, TNF-α, and type-2 biomarker [34]. Further, the short course of PD does not lower the overall immunity, and hypersensitivity reactions are less common than methylprednisolone [5]. If oral PD is administered at an earlier stage of infection, fewer side effects will develop, since the inflammatory cascade might be overcome at a lower dose of PD.