> top > docs > PMC:7335631 > spans > 1475-4531 > annotations

PMC:7335631 / 1475-4531 JSONTXT

Annnotations TAB JSON ListView MergeView

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T18 116-119 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T19 289-297 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T20 586-594 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T21 690-698 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T22 780-784 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T23 811-818 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T24 861-869 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T25 1037-1044 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T26 1106-1113 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T27 1146-1154 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T28 1195-1203 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T29 1231-1235 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T30 1236-1244 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T31 1259-1266 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T32 1286-1297 Body_part denotes amino acids http://purl.org/sig/ont/fma/fma82739
T33 1451-1458 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T34 1496-1510 Body_part denotes tight junction http://purl.org/sig/ont/fma/fma67397
T35 1522-1529 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T36 1637-1647 Body_part denotes Amino acid http://purl.org/sig/ont/fma/fma82739
T37 1685-1692 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T38 1776-1786 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T39 2003-2010 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T40 2170-2178 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T41 2272-2279 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T42 2350-2357 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T43 2358-2365 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T44 2420-2430 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T45 2431-2433 Body_part denotes A1 http://purl.org/sig/ont/fma/fma66592
T46 2440-2450 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T47 2451-2453 Body_part denotes A2 http://purl.org/sig/ont/fma/fma66595
T48 2516-2526 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T49 2624-2631 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T50 2718-2725 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T51 2774-2778 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T52 2785-2792 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T53 2894-2901 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T54 2951-2958 Body_part denotes genomes http://purl.org/sig/ont/fma/fma84116

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T8 54-87 Disease denotes Severe Acute Respiratory Syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T9 89-97 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T10 126-130 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T11 305-309 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T12 598-602 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T13 1270-1274 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T14 1382-1385 Disease denotes TMD http://purl.obolibrary.org/obo/MONDO_0005473|http://purl.obolibrary.org/obo/MONDO_0008040|http://purl.obolibrary.org/obo/MONDO_0010870
T17 1462-1466 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T18 1696-1700 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T19 2014-2018 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T20 2046-2050 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T21 2186-2190 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T22 2200-2204 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T23 2283-2287 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T24 2297-2301 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T25 2369-2373 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T26 2635-2639 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T27 2807-2816 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T28 2905-2909 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T29 2941-2945 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T3 120-125 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T4 188-189 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T5 320-321 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T6 399-405 http://purl.obolibrary.org/obo/CLO_0001302 denotes 3], [4
T7 454-459 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T8 633-641 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T9 761-766 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T10 774-784 http://purl.obolibrary.org/obo/CLO_0053065 denotes human cell
T11 905-910 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T12 1163-1171 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T13 1231-1235 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T14 1481-1486 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T15 1494-1495 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T16 1502-1510 http://purl.obolibrary.org/obo/UBERON_0007651 denotes junction
T17 1591-1601 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T18 2057-2058 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T19 2100-2106 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T20 2108-2112 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bats
T21 2451-2453 http://purl.obolibrary.org/obo/CLO_0001562 denotes A2
T22 2774-2778 http://purl.obolibrary.org/obo/GO_0005623 denotes cell

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T10 289-297 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T11 550-554 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T12 586-594 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T13 690-698 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T14 811-818 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T15 861-869 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T16 1037-1044 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T17 1106-1113 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T18 1146-1154 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T19 1195-1203 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T20 1236-1244 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T21 1259-1266 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T22 1286-1297 Chemical denotes amino acids http://purl.obolibrary.org/obo/CHEBI_33709
T23 1286-1291 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T24 1292-1297 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T25 1451-1458 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T26 1522-1529 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T27 1637-1647 Chemical denotes Amino acid http://purl.obolibrary.org/obo/CHEBI_33704
T28 1643-1647 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T29 1685-1692 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T30 1776-1786 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T31 1776-1781 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T32 1782-1786 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T33 2003-2010 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T34 2170-2178 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T35 2272-2279 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T36 2350-2357 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T37 2358-2365 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T38 2420-2430 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T39 2420-2425 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T40 2426-2430 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T41 2440-2450 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T42 2440-2445 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T43 2446-2450 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T44 2516-2526 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T45 2516-2521 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T46 2522-2526 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T47 2624-2631 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T48 2718-2725 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T49 2785-2792 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T50 2894-2901 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 1382-1385 Phenotype denotes TMD http://purl.obolibrary.org/obo/HP_0005534

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 941-948 http://purl.obolibrary.org/obo/GO_0007114 denotes budding
T2 959-968 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T3 974-986 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T4 1048-1060 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T5 1591-1610 http://purl.obolibrary.org/obo/GO_0001738 denotes epithelial polarity

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T15 0-15 Sentence denotes 1 Introduction
T16 16-240 Sentence denotes The present pandemic situation of the Severe Acute Respiratory Syndrome (COVID-19) is caused by the RNA virus SARS-CoV2 which is characterized by its rapid mutations up to a million times higher than that of their hosts [1].
T17 241-408 Sentence denotes Several mutations have been detected in various proteins of the SARS-CoV2 over a short period of time, which are recently reported in various articles [[2], [3], [4]].
T18 409-490 Sentence denotes Genomic variations and evolution enabled the virus to escape host immunity [5,6].
T19 491-571 Sentence denotes So, such variability would help the scientists towards the drug development [1].
T20 572-789 Sentence denotes Among various proteins of SARS-CoV2, spike(S), envelope (E), membrane(M) and nucleocapsid (N) are the four structural proteins which help them in assembling and releasing new copies of the virus within human cell [7].
T21 790-991 Sentence denotes The CoV envelope (E) protein is the smallest among the four structural proteins involved in several aspects of the virus life cycle, such as assembly, budding, envelope formation, and pathogenesis [7].
T22 992-1091 Sentence denotes However, the molecular mechanism involving E-protein in pathogenesis is not yet clearly understood.
T23 1092-1208 Sentence denotes Notably, this protein interacts with other structural proteins such as membrane(M) and other accessory proteins viz.
T24 1209-1249 Sentence denotes ORF3a, ORF7a and host cell proteins [8].
T25 1250-1414 Sentence denotes Envelope protein of SARS-CoV2 is 76 amino acids long and possesses three important domains viz. (N)-terminus, transmembrane domain (TMD) and (C)-terminus (Fig. 1 ).
T26 1415-1629 Sentence denotes The (C)-terminal domain of envelope protein in SARS-CoV2 binds to human PALS1, a tight junction-associated protein, which is essential for the establishment and maintenance of epithelial polarity in mammals [9,10].
T27 1630-1710 Sentence denotes Fig. 1 Amino acid sequence and domains of the envelope protein of SARS-CoV2 [7].
T28 1711-1932 Sentence denotes Red and blue colors are representing hydrophobic and hydrophilic amino acid, respectively. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)
T29 1933-2139 Sentence denotes Four mutations including one deletion have been found in the envelope protein of SARS-CoV2 with reference to the SARS-CoV1, a species of coronavirus that also infects humans, bats and certain other mammals.
T30 2140-2230 Sentence denotes The alignment of the envelope proteins of the SARS-CoV1 and SARS-CoV2 is given in Fig. 2 .
T31 2231-2307 Sentence denotes Fig. 2 Clustal alignment of the envelope protein of SARS-CoV1 and SARS-CoV2.
T32 2308-2659 Sentence denotes Mutations in (C)-terminus domain in the E protein protein of SARS-CoV2 are T55S, V56F, E69R (the mutation of an amino acid A1 to an amino acid A2 is denoted by A1pA2 where p denotes location in the reference amino acid sequence).The deletion mutation of G at the 70th position with respect to the reference envelope protein of SARS-CoV1 is also noted.
T33 2660-2827 Sentence denotes It is reported that the C-terminus domain of the envelope protein contains the motif DLLV which binds to the host cell PALS1 protein to facilitate infection [9,11,12].
T34 2828-3056 Sentence denotes In this present study, non-synonymous mutations over the envelope protein of SARS-CoV2 across the available 3617 SARS-CoV2 genomes (as on 6th June 2020), have been found and accordingly their probable consequences are discussed.

2_test

Id Subject Object Predicate Lexical cue
32640274-32576227-44882416 237-238 32576227 denotes 1
32640274-19394665-44882417 394-395 19394665 denotes 2
32640274-18452964-44882418 487-488 18452964 denotes 6
32640274-32576227-44882419 568-569 32576227 denotes 1
32640274-31133031-44882420 786-787 31133031 denotes 7
32640274-31133031-44882421 988-989 31133031 denotes 7
32640274-25105276-44882422 1246-1247 25105276 denotes 8
32640274-20861307-44882423 1623-1624 20861307 denotes 9
32640274-30712672-44882424 1625-1627 30712672 denotes 10
32640274-31133031-44882425 1707-1708 31133031 denotes 7
32640274-20861307-44882426 2818-2819 20861307 denotes 9
32640274-15513994-44882427 2820-2822 15513994 denotes 11

LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T38 89-97 SP_7 denotes COVID-19
T39 116-119 BV_22 denotes RNA
T40 120-125 BV_22;NCBITaxon:10239 denotes virus
T41 126-135 SP_7 denotes SARS-CoV2
T42 305-314 SP_7 denotes SARS-CoV2
T43 409-416 SO:0001026 denotes Genomic
T44 454-459 NCBITaxon:10239 denotes virus
T45 550-554 CHEBI:23888;CHEBI:23888;GO:0017144 denotes drug
T46 555-566 GO:0017144 denotes development
T47 598-607 SP_7 denotes SARS-CoV2
T48 619-627 GO:0031975 denotes envelope
T49 633-641 GO:0016020 denotes membrane
T50 649-661 GO:0019013 denotes nucleocapsid
T51 761-766 NCBITaxon:10239 denotes virus
T52 774-779 SP_6;NCBITaxon:9606 denotes human
T53 794-797 NCBITaxon:11886 denotes CoV
T54 798-806 GO:0031975 denotes envelope
T55 905-910 NCBITaxon:10239 denotes virus
T56 941-948 GO:0007114 denotes budding
T57 950-958 GO:0031975;GO:0070841 denotes envelope
T58 959-968 GO:0070841 denotes formation
T59 1035-1044 PG_2 denotes E-protein
T60 1163-1171 GO:0016020 denotes membrane
T61 1270-1279 SP_7 denotes SARS-CoV2
T62 1333-1340 SO:0000417 denotes domains
T63 1360-1373 GO:0016020 denotes transmembrane
T64 1374-1380 SO:0000417 denotes domain
T65 1432-1438 SO:0000417 denotes domain
T66 1442-1450 GO:0031975 denotes envelope
T67 1462-1471 SP_7 denotes SARS-CoV2
T68 1481-1486 SP_6;NCBITaxon:9606 denotes human
T69 1487-1492 PR:000010546 denotes PALS1
T70 1591-1601 UBERON:0000483 denotes epithelial
T71 1614-1621 NCBITaxon:40674 denotes mammals
T72 1661-1668 SO:0000417 denotes domains
T73 1676-1684 GO:0031975 denotes envelope
T74 1696-1705 SP_7 denotes SARS-CoV2
T78 1994-2002 GO:0031975 denotes envelope
T79 2014-2023 SP_7 denotes SARS-CoV2
T80 2046-2055 SP_10 denotes SARS-CoV1
T81 2059-2066 NCBITaxon:species denotes species
T82 2070-2081 NCBITaxon:11118 denotes coronavirus
T83 2100-2106 NCBITaxon:9606 denotes humans
T84 2108-2112 SP_2;NCBITaxon:6960 denotes bats
T85 2131-2138 NCBITaxon:40674 denotes mammals
T86 2161-2169 GO:0031975 denotes envelope
T87 2186-2195 SP_10 denotes SARS-CoV1
T88 2200-2209 SP_7 denotes SARS-CoV2
T89 2263-2271 GO:0031975 denotes envelope
T90 2283-2292 SP_10 denotes SARS-CoV1
T91 2297-2306 SP_7 denotes SARS-CoV2
T92 2334-2340 SO:0000417 denotes domain
T93 2348-2357 PG_2 denotes E protein
T94 2369-2378 SP_7 denotes SARS-CoV2
T95 2615-2623 GO:0031975 denotes envelope
T96 2635-2644 SP_10 denotes SARS-CoV1
T105 2695-2701 SO:0000417 denotes domain
T106 2709-2717 GO:0031975 denotes envelope
T107 2779-2784 PR:000010546 denotes PALS1
T108 2885-2893 GO:0031975 denotes envelope
T109 2905-2914 SP_7 denotes SARS-CoV2
T110 2941-2950 SP_7 denotes SARS-CoV2
T111 2951-2958 SO:0001026 denotes genomes
T28 2905-2914 SP_7 denotes SARS-CoV2
T4003 12-21 SP_7 denotes ion The p
T18107 74-82 GO:0031975 denotes tory Syn
T6390 94-103 SP_10 denotes -19) is c
T41142 108-117 SP_7 denotes by the R
T39336 142-148 SO:0000417 denotes is cha
T17882 156-165 PG_2 denotes ed by its
T79720 179-188 SP_7 denotes ns up to
T60117 424-432 GO:0031975 denotes ons and
T86132 444-453 SP_10 denotes abled the
T97 508-516 GO:0031975 denotes ity woul
T98 528-537 SP_10 denotes cientists
T99 542-551 SP_7 denotes rds the d
T100 577-583 SO:0000417 denotes vario
T101 591-600 PG_2 denotes ins of SA
T102 613-622 SP_7 denotes e(S), env
T103 861-869 GO:0031975 denotes proteins
T104 881-890 SP_10 denotes several
T48202 940-946 SO:0000417 denotes buddi
T11124 954-962 GO:0031975 denotes lope for
T62284 1024-1029 PR:000010546 denotes invo
T12808 1129-1137 GO:0031975 denotes other st
T59333 1149-1158 SP_7 denotes teins suc
T73384 1185-1194 SP_7 denotes accessory
T64465 1195-1202 SO:0001026 denotes protein
T41804 1325-1330 NCBITaxon:10239 denotes porta
T36342 1376-1385 SP_7 denotes main (TMD
T76846 1386-1393 SO:0001026 denotes and (C
T53341 1442-1450 GO:0031975 denotes envelope
T98716 1462-1471 SP_7 denotes SARS-CoV2
T92867 1724-1729 NCBITaxon:10239 denotes color
T20227 1730-1737 SO:0001026 denotes are re
T39059 1926-1935 PG_2 denotes icle.) Fo
T34504 1969-1978 SP_7 denotes n have be
T97111 1979-1986 SO:0001026 denotes n found
T76196 2046-2053 SO:0001026 denotes SARS-Co
T44455 2187-2195 GO:0031975 denotes ARS-CoV1
T1151 2208-2217 SP_7 denotes 2 is give
T75613 2218-2225 SO:0001026 denotes in Fig
T76504 2516-2525 SP_7 denotes amino aci
T40061 2526-2533 SO:0001026 denotes sequen
T30316 2539-2548 PG_2 denotes e deletio
T756 2633-2639 SO:0000417 denotes f SARS
T39548 2773-2781 GO:0031975 denotes cell PA
T32948 2898-2907 SP_10 denotes ein of SA
T64365 2917-2924 SO:0001026 denotes ross th