Currently, the recommended daily intake of n-3 PUFAs varies as regarding expert committees, ranging from 250 to 500 mg for healthy adults (Flock et al., 2013). The European Food Safety Authority's (EFSA) recommendation is 250 mg/day n-3 PUFAs (EPA and DHA) for adult males and non-pregnant females, and supplementation of 100–200 mg/day of DHA in pregnancy (EFSA Panel on Dietetic Products, 2010). For children less than 2 years old, the daily recommendation corresponds to 100 mg DHA, while for children more than 2 years and in adolescents, the daily recommendation is similar to that for adults (EFSA Panel on Dietetic Products, 2010). The upper daily value of acceptable for EPA and DHA consumption has been set at 2000 mg, but higher doses used in clinical trials did not induce adverse effects (Rangel-Huerta et al., 2012).