Moderate-carbohydrate versus low-fat diet Randomised controlled trial 122 overweight and obese adults 6-month diet intervention:➢ Group 1: moderate-carbohydrate and high-glycaemic index (GI) diet (HGI), n = 37 ➢ Group 2: a moderate-carbohydrate and low-GI diet (LGI), n = 36 ➢ Group 3: a low-fat and high-GI diet (LF), n = 31 LGI vs LF: ↓ fasting insulin, ↑ HOMANo significant differences among groups regarding lipid profiles, inflammatory and metabolic risk markers (IL-6, MCP-1, Leptin, ICAM-1). Juanola-Falgarona et al. (2014)