Low carbohydrate high fat, diet Randomised controlled trial 55 obese subjects 12-week diet intervention:➢ High-fat, low-carbohydrate diet (HFLC) group ➢ Low-fat, high-carbohydrate diet (LFHC) group HFLC: ↓ CRP,TG ↑ adiponectin, HDL Ruth et al. (2013)