Switching to an isocaloric ketogenic diet (KD) Clinical study 17 men (BMI: 25–35 kg/m2) Transitioning from a normal diet (4 weeks–35% fat, 15% protein, 50% carbohydrate) to 4 weeks of an isocaloric KD (80% fat, 5% carbohydrate, 15% protein) KD: ↑glycerol, free fatty acids, glucagon, adiponectin, gastric inhibitory peptide, TC, LDL, CRP↓Fasting insulin, C-peptide, triglycerides and fibroblast growth factor 21 Rosenbaum et al. (2019)