Randomized cross-over trial 50 Danish subjects with high risk of metabolic syndrome two 8-week periods of whole grain intake (179 ± 50 g/day)/refined grain (maximum 13 ± 10 g/day of whole grain), divided by a washout period of ≥6 weeks. ↓ body weight, serum inflammatory markers (IL-6, CRP) Roager et al. (2019)