Limitations of Study
A limitation of the current study is the use of a non-human cell line for proteomics analysis upon SARS-CoV-2 infection; here, an African green monkey cell line (Vero E6) was used because it has been shown previously to be highly permissible to SARS-CoV-2 infection (Harcourt et al., 2020). However, pharmacological inhibition of SARS-CoV-2 was assessed in human lung A549-ACE2 cells in addition to Vero E6 cells. The majority of drug effects were found to be replicated between cell lines.