Pharmacological profiling dose response analysis
A hill function was fit to each dose response curve using the lsqcurvefit function in MATLAB (R2018a). IC50 (virus) and CC50 (cell viability) values were defined as the concentration at which the percent measure (virus or cell viability quantification) crossed the 50% mark. If the fit curve did not begin above 50% and cross to below 50% throughout the dose response, an IC50 or CC50 value was marked as greater than the maximum tested concentration. For TCID50 and plaque assay results, which are not depicted in a percent scale, the IC50 values were extracted directly from the parameterized hill equation (see Figure S5 and Table S8).