(B) Boxplots illustrate sum of all GM3s (p = 0.0037), and three representatives, GM3 d18:0/26:0 (p = 0.0008), GM3 d18:1/16:0 (p = 0.0017), and GM3 d18:1/24:1 (p = 0.0015), that displayed increasing trends in isolated exosomes from healthy controls to COVID-19 patients of increasing severity.